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本帖最后由 蓝鱼o_0 于 2012-11-22 00:07 编辑
Antimicrobial stewardship programs reduced length of hospital stays
视频地址:http://www.healio.com/infectious-disease/nosocomial-infections/news/online/%7BDD6AA971-5AE6-41F3-A7FB-7007B75D9C09%7D/Antimicrobial-stewardship-programs-reduced-length-of-hospital-stays
SAN DIEGO — Antimicrobial stewardship programs significantly reduced the hospital length of stays among patients with acute bacterial skin and skin structure infections, researchers reported here at ID Week 2012.
Thomas File
“Application of antimicrobial stewardship resulted in better outcomes for our patients with cellulitis,” Thomas File, MD, an Infectious Disease News Editorial Board member, said in an interview. “Reduced length of stay and reduced readmission rate are of relevance to patients and payers alike and has significant implication for institution reimbursement.”
File and colleagues from Summa Health System in Akron, Ohio, researchers evaluated patients admitted to the hospital with acute bacterial skin and skin structure infections. The patients were identified by the ED admission list. Patients’ clinical status and antimicrobial therapy regimen were prospectively reviewed by a pharmacist and an infectious disease specialist, who then provided feedback to the attending physician. The study began in February and is ongoing. To date, there have been 62 patient interventions. The most common infection was cellulitis, affecting 76% of the patients, followed by major or deep abscesses, comprising 26% of the patients. The remainder of the infections were surgical site infections and diabetic wounds. There were 85 interventions total. The interventions included the following: dose change (44%); dose escalation (37%); antibiotic regimen change (24%); other intervention (11%); and infectious disease consult (7%). Almost all of the interventions (95%) were accepted. The patient length of stay was 4.4 days compared with a historical average of 6.2 days (P<.001). At 30 days, the readmission rate for the patients was 3% compared with a 6% rate from historical data. “Our experience reinforces the benefit of an antimicrobial stewardship program, first and foremost for improving patient outcomes and secondarily for reducing cost,” File said. “Reducing unnecessary use of broad-spectrum agents should also reduce adverse events and selection for emergence of resistance.”
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