美国耐药菌导致的医院感染对患者死亡率的影响

David

Clinical Infectious Diseases 2008;47:927–930

BRIEF REPORT
The Impact of Antimicrobial-Resistant, Health Care–Associated Infections on Mortality in the United States
美国耐药菌导致的医院感染对患者死亡率的影响
R. Monina Klevens,1
Jonathan R. Edwards,2 and
R. P. Gaynes,2,3 for the
National Nosocomial Infections Surveillance System

Divisions of 1Viral Hepatitis and 2Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, and 3Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia

We used data reported from US hospitals to the National Nosocomial Infection Surveillance System of the Centers for Disease Control and Prevention for 3 specific infections: Staphylococcus aureus bloodstream infections, Pseudomonas aeruginosa pneumonias, and Escherichia coli urinary tract infections. We evaluated the proportion of infections with antimicrobial-resistant isolates and the relative risk of death associated with the resistant pathogen in the period 2000–2004, compared with the period 1990–1994. The proportion of antimicrobial-resistant infections increased, but there was no change in the relative risk of death between the 2 periods.

Received 14 April 2008; accepted 29 May 2008; electronically published 27 August 2008.