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关于抗生素的思考:现状如何?前进的方向?

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发表于 2012-8-31 11:58 | 显示全部楼层 |阅读模式

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The Journal of Antibiotics (2012) 65, 385–395
& 2012 Japan Antibiotics Research Association All rights reserved 0021-8820/12

Thoughts and facts about antibiotics: Where we are
now and where we are heading
This article has been corrected since advance Online Publication, and a corrigendum is also printed in this issue.
Ja´nos Be´rdy
The declining trends in microbial metabolite and natural products research and the refocusing of this research area are
discussed. Renewing natural products research requires inexhaustible natural resources, as well as new genetic techniques and
microbial sources, including endophytic microbes. The numbers of known bioactive metabolites are summarized according to
their microbiological origin, biological activities and chemical structures. Synthetic and natural product-based libraries are also
compared. Importantly, the wide range of microbial metabolite bioactivities, future trends and the importance of prioritizing
natural products over synthetic compounds are emphasized.
The Journal of Antibiotics (2012) 65, 385–395; doi:10.1038/ja.2012.27; published online 18 April 2012
Keywords: antibiotics; bioactive microbial metabolites; biodiversity; future prospects; non-antibiotic bioactivities; taxonomic diversity
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 楼主| 发表于 2012-8-31 11:59 | 显示全部楼层
附上全文:)

有兴趣的可以看看全文

Thoughts and facts about antibiotics.pdf

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发表于 2012-8-31 14:10 | 显示全部楼层
下载后英语水平有限看不明白。
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发表于 2012-8-31 14:21 | 显示全部楼层
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