对人类肠病毒长达八年的分子分型鉴定

David

Journal of Clinical Microbiology, July 2008, p. 2410-2413, Vol. 46, No. 7


Eight Years of Experience with Molecular Identification of Human Enteroviruses
对人类肠病毒长达八年的分子分型鉴定
Soile Blomqvist,* Anja Paananen, Carita Savolainen-Kopra, Tapani Hovi, and Merja Roivainen
Enterovirus Laboratory, Department of Viral Diseases and Immunology, National Public Health Institute (KTL), Helsinki, Finland

Received 14 February 2008/ Returned for modification 25 March 2008/ Accepted 24 April 2008

We have successfully typed 1,121 human enterovirus (HEV) isolates during the last 8 years by adapting partial VP1 sequencing to routine identification of HEV isolated from diverse clinical and environmental specimens. The isolates include 48 of the 59 traditional nonpoliovirus HEV serotypes and members of 8 newly discovered types, which would have remained untypeable by neutralization using the conventional cross-sectional pools of antisera.