MRSA检出情况有奖调查

细菌耐药

最近，《医院感染预防与控制最佳实践丛书》正在紧张地进行中。根据专家审稿意见，《多重耐药》分册需要补充多重耐药菌在各个地区或国家所占的百分比的最新资料。因此，需要查阅大量文献，特开此贴，有奖征集相关的文献。

本贴调查MRSA占金黄色葡萄球菌的比例，共需要收集美国、英国、日本、印度和中国的数据。

文献要求：以大型监测数据或多中心流调为主，尽量查阅最新的数据，目前应该以2009年或2010年的数据为主，2011年的数据肯定还没有发表成文。将文献题目、摘要、发表期刊、年份及相关的“MRSA占金黄色葡萄球菌的比例”的数据以回贴的形式发出。

欢迎大家积极参与本活动，加分鼓励，谢谢！

米奇朋克

Mohnarin 2008年度报告_葡萄球菌和肠球菌耐药监测.pdf (383.79 KB, 下载次数: 12)

2012-3-7 13:19 上传

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细菌耐药

mickeypank 发表于 2012-3-7 13:19

                               
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谢谢您的支持，加分鼓励！

有两点注意一下：

1. 请将文献中的数据，根据所调查的要求把核心数据提取出来，方便大家学习与交流，谢谢！
2. 尽量查找2009年和2010年的数据，如果实在没有，2008年的数据也可以的，谢谢！

再次感谢您的支持，期待您进一步的资料。

米奇朋克

细菌耐药 发表于 2012-3-7 13:23

                               
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谢谢您的支持，加分鼓励！

有两点注意一下：

知道了，不客气。你发的四个帖子，我再帮你搜索一下是否有其他国家的文献。

细菌耐药

mickeypank 发表于 2012-3-7 13:27

                               
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知道了，不客气。你发的四个帖子，我再帮你搜索一下是否有其他国家的文献。

非常感谢您的支持，所有回贴一律加分鼓励，谢谢！

sebastienkitty

Nosocomial bloodstream infection in patients caused by Staphylococcus aureus.pdf (207.65 KB, 下载次数: 1)

2012-3-7 13:58 上传

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匆匆看了下，这是篇文章搜集的是2006-2011年上半年金葡菌所致血流感染资料，其中MRSA占63.6%。

sebastienkitty

Methicillin-resistant Staphylococcus aureus infection is associated with increas.pdf (286.3 KB, 下载次数: 1)

2012-3-7 15:06 上传

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In the present study by Hanberger et al. [11],the authors evaluated a large cohort of patients
(13,796) from an extended and geographically diverse array of hospitals (1265 from 75 countries).
Their analysis is based on the 1‑day pointprevalence EPIC II study, which showed that approximately 51% of patients were infected,20.5% of them with S. aureus, with an MRSA rate of approximately 50% [12]

这篇文章引用的资料来自 Hanberger H, Walther S, Leone M et al.Increased mortality associated with
metihcillin-resistant Staphylococcus aureus (MRSA) infection in the intensive care unit:results from the EPIC II study. Int.J. Antimicrob. Agents 38(4), 331–335 (2011).

但是他们的研究数据来自2007年，不知道是否有用

sebastienkitty

MRSA prevalence in european healthcare settings a view.pdf (261.34 KB, 下载次数: 1)

2012-3-7 16:01 上传

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BMC Infect Dis. 2011 May 20;11:138. doi: 10.1186/1471-2334-11-138.MRSA prevalence in European healthcare settings: a review.

Abstract
BACKGROUND: During the past two decades, methicillin-resistant Staphylococcus aureus (MRSA) has become increasingly common as a source of nosocomial infections. Most studies of MRSA surveillance were performed during outbreaks, so that results are not applicable to settings in which MRSA is endemic. This paper gives an overview of MRSA prevalence in hospitals and other healthcare institutions in non-outbreak situations in Western Europe.

METHODS: A keyword search was conducted in the Medline database (2000 through June 2010). Titles and abstracts were screened to identify studies on MRSA prevalence in patients in non-outbreak situations in European healthcare facilities. Each study was assessed using seven quality criteria (outcome definition, time unit, target population, participants, observer bias, screening procedure, swabbing sites) and categorized as 'good', 'fair', or 'poor'.

RESULTS: 31 observational studies were included in the review. Four of the studies were of good quality. Surveillance screening of MRSA was performed in long-term care (11 studies) and acute care (20 studies). Prevalence rates varied over a wide range, from less than 1% to greater than 20%. Prevalence in the acute care and long-term care settings was comparable. The prevalence of MRSA was expressed in various ways - the percentage of MRSA among patients (range between 1% and 24%), the percentage of MRSA among S. aureus isolates (range between 5% and 54%), and as the prevalence density (range between 0.4 and 4 MRSA cases per 1,000 patient days). The screening policy differed with respect to time points (on admission or during hospital stay), selection criteria (all admissions or patients at high risk for MRSA) and anatomical sampling sites.

CONCLUSIONS: This review underlines the methodological differences between studies of MRSA surveillance. For comparisons between different healthcare settings, surveillance methods and outcome calculations should be standardized.