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J Antimicrob Chemother. 2008 Jun 12. [Epub ahead of print] Links
Interventions to control MRSA: high time for time-series analysis?
时间序列分析对如何控制MRSA的传播正当时?
Harbarth S, Samore MH.
Infection Control Program, University of Geneva Hospitals and Medical School, CH-1211 Geneva 14, Switzerland.
Time-series methods are useful in quasi-experimental study designs in which rates of antibiotic-resistant infections are ascertained before and after an intervention. However, uncertainties remain regarding the use of time-series analysis as an appropriate research methodology for analysing the effect of infection control interventions and antibiotic policies on the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA). In particular, there is still a substantial gap in our understanding of what actually happens to MRSA incidence when a planned intervention is made on use of one or more antibiotic drug classes.
PMID: 18556707 [PubMed - as supplied by publisher
Interventions to control MRSA--high time for time-series analysis.pdf
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