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Distribution of Antiseptic Resistance Genes qacA, qacB, and smr in Methicillin-Resistant Staphylococcus aureus Isolated in Toronto, Canada, from 2005 to 2009
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, June 2011, p. 2999–3001
Jean Longtin,1,2* Christine Seah,1 Krystal Siebert,1 Allison McGeer,3 Andrew Simor,4 Yves Longtin,2
Donald E. Low,1,3 and Roberto G. Melano1,3
Ontario Agency for Health Protection and Promotion, Public Health Laboratories, Toronto, ON, Canada1; Laval University
Infectious Diseases Research Center, Quebec, Canada2; Department of Microbiology, Mount Sinai Hospital, Toronto,
ON, Canada3; and Department of Microbiology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada4
Decreased susceptibility to chlorhexidine gluconate (CHDN) in methicillin-resistant Staphylococcus aureus
(MRSA) is associated with the qacA, qacB, and smr genes, encoding efflux pumps. A total of 334 MRSA isolates
were collected from two Canadian intensive care units between 2005 and 2009. We identified the qacAB genes
in 7 strains (2%; 2 qacA genes and 5 qacB genes) and the smr gene in 23 (7%) strains. CHDN minimal
bactericidal concentrations were slightly higher for strains harboring smr genes.
2999.pdf
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发表于 2011-11-2 12:44
发表于 2011-11-2 14:53
