Patients were categorized by hospital-associated CDI (HACDI), defined as new-onset diarrhea associated with CDI occurring in the long-term care facility for more than 4 days after hospital admission and within 30 days after discharge, or a long-term care facility-associated CDI (LACDI), defined as new-onset diarrhea associated with CDI that occurred more than 30 days after admission in those with no episodes of CDI within the prior 3 months, according to the report.【定义】
Compared with 59.3% of patients with an HACDI, 40.7% patients had an LACDI. Median age was 74 years among HACDI patients and 77 years among LACDI patients (P=.055). 说明两组可比。The annual rate for CDI differed between 0.11 and 0.23/1,000 resident-days for HACDI patients and between 0.04 and 0.28/1,000 resident-days for LACDI patients, the researchers wrote.
At 6-month follow-up, results indicated that LACDI patients were more likely to have a CDI relapse (48.5%) vs. HACDI patients (29.2%; P=.009). LACDI病患更容易复发。具体的说,LACDI的病患通常年龄更大,并且治疗后更容易复发。
“Patients acquiring C. difficile infection in long-term care tend to be older and are more prone to have relapses after therapy,” Muder, of the infectious disease section at VA Pittsburgh Healthcare System, told Infectious Disease News. “Control of CDI in long-term care will require control of transmission in both the acute care facilities from which patients are transferred and long-term care facilities.”
Disclosure: The researchers report no relevant financial disclosures.