E. coli o 104 h4【大肠杆菌。104 h4】

tkn5520

这两天实验室下发了E. coli o 104 h4 参考protocol。出处于www.ehec.org. 首页红色字体链接既是。可惜是德文， 大概的意斯如下：
this is an ehec stain, also called STEC (MISSSING EAE GENE).
THIS IS  AN O104 H4 ISOLATE, MLST type ST676.
it is a sorbitol fermeting isolate.
seems to bear esbl and grows on convential esbl ssceening agars.
ciprofloxacin and amionoglycosides are sensitive.
the disease and the pathogen are notifiable.
the outbreak strain was detected incases of bloody and non bloody diarrhoes, haem colitis and HUS. WOMEN PREDOMINANT.
ALSO NEUROL SEQUELAE.
THE NEXT PAGE CONTAINS A PCR PROTOCOL OF THE SPECIFICD DETECTION  .
IF ALL 4 GENES ARE DETECTED, THEN THE STRAIN IS HIHGLY LIKELY.

值得提的是：一 无血便也有可能。 二 女性为主。三 CIP GM SENS
目前我们的做法是发现从德国回来的腹泻病人，分拣一部分送ESR 用pcr 检测。昨天收了一个，已报送。后续跟踪中。。。

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    期待检测结果!

tkn5520

仅做一下更新. 目前认为是STEC 但兼有EAEC 的特征(靠adherence facter 侵入). 实验室使用EIA shiga toxin kit, esbl screen, pcr 确认. 治疗时切不可使用抗生素.