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EDITORIAL
Methicillin-resistant Staphylococcus aureus: risk assessment and infection control policies
对MRSA的风险评估和相关感控政策
E. TacconelliDepartment of Infectious Diseases, Catholic University, Rome, Italy
Corresponding author and reprint requests: E. Tacconelli, Istituto Clinica Malattie Infettive, Università Cattolica, L.go F. Vito 8, 00164 Rome, Italy
E-mail: etacconelli@rm.unicatt.it
ABSTRACT
The endemic state of methicillin-resistant Staphylococcus aureus (MRSA) occurs through a constant influx of MRSA into the healthcare setting from newly admitted MRSA-positive patients, followed by cross-transmission among inpatients and an efflux of MRSA from the hospital with discharged patients. To date, most MRSA prevention strategies have targeted cross-transmission among hospitalised patients. Intensive concerted interventions that include isolation can reduce the MRSA incidence substantially. However, debate continues about the cost-effectiveness of infection control policies, including screening protocols, to control the influx of MRSA into hospitals. The rationale and cost-effectiveness of wide screening, as compared to targeted screening, should be further studied using appropriate statistical approaches and economic modelling.
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