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RESEARCH ARTICLE
Persistence of Legionella in hospital water supplies and nosocomial Legionnaires' disease
医院供水系统的军团菌和医院内军团病的发生（来自Spain的报告）
Marian Garcia-Nuñez11Infectious Diseases Unit, Fundació Institut d'Investigació Germans Trias i Pujol, Autonomous University of Barcelona, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, Spain; and , Nieves Sopena11Infectious Diseases Unit, Fundació Institut d'Investigació Germans Trias i Pujol, Autonomous University of Barcelona, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, Spain; and , Sonia Ragull11Infectious Diseases Unit, Fundació Institut d'Investigació Germans Trias i Pujol, Autonomous University of Barcelona, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, Spain; and , Maria Luisa Pedro-Botet11Infectious Diseases Unit, Fundació Institut d'Investigació Germans Trias i Pujol, Autonomous University of Barcelona, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, Spain; and , Josep Morera22Department of Pneumology, Fundació Institut d'Investigació Germans Trias i Pujol, Autonomous University of Barcelona, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, Spain & Miguel Sabria11Infectious Diseases Unit, Fundació Institut d'Investigació Germans Trias i Pujol, Autonomous University of Barcelona, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, Spain; and 1Infectious Diseases Unit, Fundació Institut d'Investigació Germans Trias i Pujol, Autonomous University of Barcelona, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, Spain; and 2Department of Pneumology, Fundació Institut d'Investigació Germans Trias i Pujol, Autonomous University of Barcelona, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, Spain
Abstract
The molecular epidemiology of clinical and environmental Legionella species isolates was studied in seven hospitals from 1989 to 2006. The number of environmental pulsed field gel electrophoresis (PFGE) patterns ranged from one to nine according to the hospital. Genomic PFGE pattern persistence was observed in 71% of the hospitals, even after 17 years in some hospitals, and the relationship between environmental and clinical isolates was established. The isolates associated with hospital-acquired Legionnaires' disease corresponded to the persistent environmental PFGE patterns of Legionella pneumophila in potable water supplies.
j.1574-695x.2007.00362.x.pdf
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发表于 2008-2-19 16:36