美国社区相关MRSA门诊病人感染情况

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Community-associated Methicillin-Resistant Staphylococcus aureus in Outpatients, United States, 1999–2006
emerging infectious disease
Volume 15, Number 12–December 2009
Abstract
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has become a major problem in US hospitals already dealing with high levels of hospital-associated MRSA (HA-MRSA). Using antimicrobial drug susceptibility data for 1999–2006 from The Surveillance Network, we characterized the relationship between outpatient and inpatient levels of CA-MRSA nationally. In outpatients, the frequency of CA-MRSA isolates has increased >7× during 1999–2006, which suggests that outpatients have become a major reservoir for CA-MRSA. However, contrary to results in other reports, although CA-MRSA increases are associated with decreases in the frequency of HA-MRSA in hospitals, the decreases are only modest. This finding suggests that instead of replacing HA-MRSA in the hospital, CA-MRSA is adding to the overall presence of MRSA already found within the hospital population.

1999–2006年美国社区相关的耐甲氧西林金黄色葡萄球菌门诊病人感染情况
Eili Klein， David L. Smith和Ramanan Laxminarayan   
社区相关的耐甲氧西林金黄色葡萄球菌（CA-MRSA）已成为美国医院的主要问题，采取和处理较高级别的医院相关的耐甲氧西林金黄色葡萄球菌（HA-MRSA）相同的方法处理。综合网络监测系统1999–2006年抗生素药物敏感资料，我们分析全国门诊病人和住院病人的CA-MRSA关系。在1999–2006年的门诊病人中，CA-MRSA分离率提高了7倍，提示门诊病人已成为CA-MRSA的主要来源。然而和其他报告相反，虽然医院的CA-MRSA升高和HA-MRSA降低相关，但HA-MRSA降低是轻微的。这个发现提示CA-MRSA没有取代医院流行的HA-MRSA，而是增加在医院内MRSA病人的的总量。

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