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，很不错。
特别是摘要的最后一句话：It is a major public health problem primarily related to health care but no longer confined to intensive care units, acute care hospitals, or any health care institution.
上一个摘要的译文吧。原谅本人才疏学浅和时间匆忙，如有不妥之处，愿听其详！
Invasive Methicillin-Resistant
Staphylococcus aureus Infections
in the United States
美国侵入性MRSA感染
Context As the epidemiology of infections with methicillin-resistant Staphylococcus
aureus (MRSA) changes, accurate information on the scope and magnitude of MRSA
infections in the US population is needed.
背景：随着MRSA感染流行病学的改变，准确获取美国人群中MRSA感染范围和等级相关信息变得越来越有必要。
Objectives To describe the incidence and distribution of invasive MRSA disease in
9 US communities and to estimate the burden of invasive MRSA infections in the United
States in 2005.
目标：对美国国内9个监测点MRSA引发疾病的发生率和分布进行描述，用以推断05年美国MRSA感染负荷情况。
Design and Setting Active, population-based surveillance for invasive MRSA in 9
sites participating in the Active Bacterial Core surveillance (ABCs)/Emerging Infections
Program Network from July 2004 through December 2005. Reports of MRSA
were investigated and classified as either health care–associated (either hospital-
onset or community-onset) or community-associated (patients without established health
care risk factors for MRSA).
设计和执行：采用活跃性细菌核心监测（ABCs)/感染暴露调查网络项目从04年7月到05年11月间所获得的群体性监测资料。了解美国9个不同监测点人群MRSA感染的监测情况。对所有非医疗相关性和非社区相关性（无卫生保健获得MRSA风险因素病人）MRSA感染的的报道进行调查和分析。
Main Outcome Measures Incidence rates and estimated number of invasive MRSA
infections and in-hospital deaths among patients with MRSA in the United States in
2005; interval estimates of incidence excluding 1 site that appeared to be an outlier
with the highest incidence; molecular characterization of infecting strains.
方法：对美国05年MRSA感染发生率、MRSA感染人数估值和医院内死于MRSA感染人数相关性进行分析。研究过程中排除了一个调查点，因为该点感染发生很可能为输入性事件。同时，对分离菌株进行分子特征性分析。
Results There were 8987 observed cases of invasive MRSA reported during the surveillance
period. Most MRSA infections were health care–associated: 5250 (58.4%)
were community-onset infections, 2389 (26.6%) were hospital-onset infections; 1234
(13.7%) were community-associated infections, and 114 (1.3%) could not be classified.
In 2005, the standardized incidence rate of invasive MRSA was 31.8 per 100 000
(interval estimate, 24.4-35.2). Incidence rates were highest among persons 65 years
and older (127.7 per 100 000; interval estimate, 92.6-156.9), blacks (66.5 per 100 000;
interval estimate, 43.5-63.1), and males (37.5 per 100 000; interval estimate, 26.839.5).
There were 1598 in-hospital deaths among patients with MRSA infection during
the surveillance period. In 2005, the standardized mortality rate was 6.3 per 100 000
(interval estimate, 3.3-7.5). Molecular testing identified strains historically associated
with community-associated disease outbreaks recovered from cultures in both hospital-
onset and community-onset health care–associated infections in all surveillance areas.
结果：监测期间，共有8987例MRSA感染报道。其中绝大部分MRSA感染病例为医疗卫生获得，在社区内发生：5250例（58.4％）；2389例（26.6％）为医院内发生；1234例（13.7％）为社区获得感染；114例无法分类。05年标准化发生率为31.8/100，000 。MRSA在以下人群高发：65岁及以上(标化发生率：127.7/100，000)，黑人(标化发生率：66.5/100，000)和男性(标化发生率：37.5/100,000)。调查期间，有1598例MRSA感染病人为医院内死亡，05年标准化死亡率为6.3％。对所9个监测点社区内爆发事件的中分离出菌株的分子学检测提示均为医院内的和社区医疗卫生服务中获得。
Conclusions Invasive MRSA infection affects certain populations disproportionately.
It is a major public health problem primarily related to health care but no longer
confined to intensive care units, acute care hospitals, or any health care institution.
结论：MRSA感染对某些人群产生危害。MRSA感染将不再限定于ICU、急救医院或公共卫生机构，而正在成为与卫生保健密切相关的重要共卫生问题之一。
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发表于 2007-11-4 15:32
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