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Infect Control Hosp Epidemiol. 2007 Jul;28(7):892-5. Epub 2007 May 31. Links
Review of clinical trials of skin antiseptic agents used to reduce blood culture contamination.Malani A, Trimble K, Parekh V, Chenoweth C, Kaufman S, Saint S.
Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, MI, USA. malanian@med.umich.edu
False-positive blood culture results may lead to prolonged hospitalization, inappropriate antibiotic administration, and increased healthcare costs. We conducted a review of the literature to assess the effect of skin antiseptic agents on the rate of false-positive blood culture results. We found no clear evidence to suggest which antiseptic should be used to prevent false-positive results. Studies suggest, however, a possible benefit from the use of prepackaged skin antiseptic kits and alcohol-containing antiseptics.
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