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Standardization of needlestick injury and evaluation of a novel virus-inhibiting protective glove
针刺伤标准化与一种新型抗病毒防护手套的评价
Journal of Hospital Infection
Volume 66, Issue 4, August 2007, Pages 339-345 Summary
Rubber surgical gloves worn as a barrier to prevent contamination from body fluids offer relative protection against contamination through direct percutaneous injuries involving needles, scalpel blades or bone fragments.橡胶外科手套是一种用来预防因针刺、手术室刀片和骨头碎片刺伤等职业伤害通过体液引起感染的阻断物 To determine the main experimental parameters influencing the volume of blood transmitted by a hollow-bore needle (worst case scenario) during an accidental puncture, we designed an automatic puncture apparatus.为获得因意外刺伤通过有孔针（最坏的情况下）进行血液传播的主要影响参数，我们设计了一个自动穿刺器具。 Herpes simplex type 1 virus (HSV1), a model for enveloped viruses, was used as a ‘marker’ in an in-vitro gelatine model.我们把一种包膜病毒单纯疱疹1型病毒作为一个标记穿刺体外明胶模型（模拟人体来获得数据） Of the experimental parameters studied, the most critical influences were found to be needle diameter and puncture depth, whereas puncture speed, puncture angle and glove-stretching feature appeared to be less influential.实验数据显示最危险的影响是针头的直径和刺伤的深度，而与针刺速度、针刺角和手套的弹性影响不大。 A single glove reduced the volume of blood transferred by 52% compared with no glove, but double gloving offered no additional protection against hollow-bore needle punctures.戴单只手套比不戴手套可以减少52%的因有孔针刺伤通过血液传播的危险性，戴双层手套没有额外增加防护效果Using ‘standardized’ puncture conditions, the virus-inhibiting surgical glove G-VIR® elicited an 81% reduction in the amount of HSV1 transmitted as compared with single or double latex glove systems. 在标准化的刺伤情况下，抗病毒防护手套比单层或双层乳胶手套减少了81%传播单纯疱疹1型病毒的危险性。
Keywords: Blood exposure accident; Needle puncture; Viral contamination; Glove; Protection
编译：
题目：针扎伤标准化与一种新型抗病毒防护手套的评价
橡胶外科手套是可以用来预防因针刺、手术室刀片和骨头碎片刺伤等职业伤害通过体液引起感染。研究者为获得因意外刺伤通过有孔针（最坏的情况下）进行血液传播的主要影响参数，设计了一个自动穿刺器具，把单纯疱疹1型病毒（一种包膜病毒）作为一个标记穿刺体外明胶模型（模拟人体来获得数据）。实验数据显示最危险的影响是针头的直径和刺伤的深度，而与针刺速度、针刺角和手套的弹性关系不大。戴单只手套比不戴手套可以减少52%的因有孔针刺伤通过血液传播的危险性，戴双层手套没有额外增加防护效果，在标准化的刺伤情况下，抗病毒防护手套比单层或双层乳胶手套减少了81%传播单纯疱疹1型病毒的危险性。 |
发表于 2007-9-13 19:55
发表于 2017-4-2 21:32