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Clinical Infectious Diseases 2009;49:000–000
© 2009 by the Infectious Diseases Society of America. All rights reserved.
1058-4838/2009/4903-00XX$15.00
DOI: 10.1086/600877
IDSA GUIDELINES
Vancomycin Therapeutic Guidelines: A Summary of Consensus Recommendations from the Infectious Diseases Society of America, the American Society of Health‐System Pharmacists, and the Society of Infectious Diseases Pharmacists
IDSA万古霉素治疗MRSA的指南
Michael J. Rybak,1,2,3
Ben M. Lomaestro,4
John C. Rotscahfer,5
Robert C. Moellering, Jr.,6,7,8
Willam A. Craig,9
Marianne Billeter,10
Joseph R. Dalovisio,11 and
Donald P. Levine3
1Anti‐Infective Research Laboratory, Department of Pharmacy Practice, College of Pharmacy & Health Sciences, and 2Department of Medicine, School of Medicine, Wayne State University, and 3Detroit Receiving Hospital & University Health Center, Detroit, Michigan; 4Albany Medical Center, Albany, New York; 5Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis; 6Shields Warren‐Mallinckrodt Medical Research, 7Harvard Medical School, and 8Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts; 9University of Wisconsin School of Medicine and Public Health, Madison; and 10Oshsner Medical Centers and 11Department of Infectious Diseases, Oschsner Health System, New Orleans, Louisiana
Practice guidelines for therapeutic monitoring of vancomycin treatment for Staphylococcus aureus infection in adult patients were reviewed by an expert panel of the Infectious Diseases Society of America, the American Society of Health‐System Pharmacists, and the Society of Infectious Diseases Pharmacists. A literature review of existing evidence regarding vancomycin dosing and monitoring of serum concentrations, in addition to patient outcomes combined with expert opinion regarding the drug’s pharmacokinetic, pharmacodynamic, and safety record, resulted in new recommendations for targeting and adjustment of vancomycin therapy.
Received 9 April 2009; accepted 10 April 2009; electronically published 1 July 2009. |
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