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Am J Surg. 2012 Dec;204(6):1021-4. doi: 10.1016/j.amjsurg.2012.10.004.Negative pressure wound therapy in the prevention of wound infection in high risk abdominal wound closures.伤口负压治疗技术预防高风险腹部手术部位感染Vargo D.
SourceDepartment of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address: daniel.vargo@hsc.utah.edu.
AbstractBACKGROUND: Wound infections continue to be an issue in abdominal surgery. Tissue perfusion may be a contributing factor. Negative pressure application may have promise in decreasing wound complication.SSI一直困扰腹部外科。组织灌注是归因危险因素之一。应用负压可能可以减少伤口并发症。
METHOD: A retrospective review of prospectively collected data in patients with high-risk abdominal wounds was undertaken. Comorbidities, risk factors for infection, wound classification, and wound outcomes were all evaluated. The primary outcome measure was wound infection rate. Secondary outcomes included device safety and overall surgical site complication rate.
回顾性复查前瞻性收集的高风险腹部手术患者的资料。评估的资料有并发症、感染危险因素、切口分类、切口愈合。测量的主要结果是SSI发生率，次要结果包括装置安全性，总的手术部位并发症发生率。RESULTS: Thirty patients were identified who had skin flaps in whom negative pressure was used. Negative pressure was applied for an average of 5.6 days (range, 5-7 days). No patient developed ischemia or necrosis of the skin flaps. No wound infections were identified. The overall wound complication rate was 3%. The comparable historical control wound complication rate was 20%, and χ(2) analysis showed a statistically significant decrease in the infection rate with negative-pressure wound therapy (P < .05).
找到了30例有皮瓣使用了负压的患者。负压平均使用5.6天（5-7天）。没有患者发生皮瓣缺血或坏死。没有患者发生SSI。总的伤口并发症发生率为3%。过去可比较的对照伤口并发症发生率为20%，卡方检验显示负压治疗组感染发生率有统计学显著减少。CONCLUSIONS: Negative-pressure wound therapy applied to a closed, high-risk surgical wound is safe, with no evidence of skin necrosis and decreased wound infection rate.负压应用于密闭、高风险外科伤口是安全的，没有皮肤坏死的证据，降低SSI发生率。
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发表于 2012-12-16 16:19
发表于 2012-12-16 18:16
