Appraising Contemporary Strategies to Combat MRGNB infection

蓝鱼o_0

【题目】Appraising Contemporary Strategies to Combat Multidrug Resistant Gram-Negative Bacterial Infections–Proceedings and Data From the Gram-Negative Resistance Summit

Clin Infect Dis, 2011年发表。Clinical Infectious Diseases 2011;53(S2):S33–S55
【摘要】
The emerging problem of antibiotic resistance, especially among Gram-negative bacteria (GNB), has become
a serious threat to global public health. Very few new antibacterial classes with activity against antibioticresistant
GNB have been brought to market. Renewed and growing attention to the development of novel
compounds targeting antibiotic-resistant GNB, as well as a better understanding of strategies aimed at preventing
the spread of resistant bacterial strains and preserving the efficacy of existing antibiotic agents, has occurred.
The Gram-Negative Resistance Summit convened national opinion leaders for the purpose of analyzing current
literature, epidemiologic trends, clinical trial data, therapeutic options, and treatment guidelines related to
the management of antibiotic-resistant GNB infections. After an in-depth analysis, the Summit investigators
were surveyed with regard to 4 clinical practice statements. The results then were compared with the same
survey completed by 138 infectious disease and critical care physicians and are the basis of this article.