手卫生与MRSA感染成本（翻译有奖）

潮水

Hand Hygiene Noncompliance and the Cost of Hospital‐Acquired Methicillin‐Resistant Staphylococcus aureus Infection
Infect Control Hosp Epidemiol 2010;31:357–364
Background.Hand hygiene noncompliance is a major cause of nosocomial infection. Nosocomial infection cost data exist, but the effect of hand hygiene noncompliance is unknown.

Objective.To estimate methicillin‐resistant Staphylococcus aureus (MRSA)‐related cost of an incident of hand hygiene noncompliance by a healthcare worker during patient care.

Design.Two models were created to simulate sequential patient contacts by a hand hygiene–noncompliant healthcare worker. Model 1 involved encounters with patients of unknown MRSA status. Model 2 involved an encounter with an MRSA‐colonized patient followed by an encounter with a patient of unknown MRSA status. The probability of new MRSA infection for the second patient was calculated using published data. A simulation of 1 million noncompliant events was performed. Total costs of resulting infections were aggregated and amortized over all events.

Setting.Duke University Medical Center, a 750‐bed tertiary medical center in Durham, North Carolina.

Results.Model 1 was associated with 42 MRSA infections (infection rate, 0.0042%). Mean infection cost was $47,092 (95% confidence interval [CI], $26,040–$68,146); mean cost per noncompliant event was $1.98 (95% CI, $0.91–$3.04). Model 2 was associated with 980 MRSA infections (0.098%). Mean infection cost was $53,598 (95% CI, $50,098–$57,097); mean cost per noncompliant event was $52.53 (95% CI, $47.73–$57.32). A 200‐bed hospital incurs $1,779,283 in annual MRSA infection–related expenses attributable to hand hygiene noncompliance. A 1.0% increase in hand hygiene compliance resulted in annual savings of $39,650 to a 200‐bed hospital.

Conclusions.Hand hygiene noncompliance is associated with significant attributable hospital costs. Minimal improvements in compliance lead to substantial savings.

lindahawk729

回复 1# 潮水
我来试一下！

黑旋风

我来试一下！

黑旋风

医院获得性耐甲氧西林金黄色葡萄球菌感染和手卫生不规范成本研究
感染控制Hosp流行病学2010; 31:357-364

背景：手卫生不规范是院内感染的重要原因。医院感染的成本数据存在的，但手卫生不遵守效力还是未知数。

目的：为了估计耐甲氧西林金黄色葡萄球菌（MRSA）的一名医护人员有关的手部卫生违规事件，在护理病人的费用。
方法设计：两个模型的建立是为了模拟一个手部卫生，不符合安全要求医护人员顺序与病人接触。模型1宗遇到与身份不明的MRSA的病人。模型2包括一个携带有葡萄球菌的病人有一名不明身份MRSA的病人接触后遇到的问题。新的MRSA感染的第二个病人概率计算公布的数据。 100万不符合安全要求的事件模拟。感染而造成的成本总额，则聚集了所有事件和摊销。
设置：杜克大学医学中心，一个750个床位的高等教育在北卡罗来纳州达勒姆市医疗中心。
结果：模型1是与42 MRSA感染（感染率，0.0042％）。平均感染成本四十七点○九二美元（95％置信区间[CI]，二万六千零四十○美元 - 68.146美元），平均费用为不符合安全要求的事件是1.98美元（95％CI为0.91美元，3.04美元）。模型2是与980 MRSA感染（0.098％）。平均感染成本五十三点五九八美元（95％CI为五万○九十八美元 - 五万七千零九十七美元），平均费用为不符合安全要求的事件是五十二点五三美元（95％CI为47.73美元-五十七点三二美元）。一个200个床位的医院招致年度MRSA感染一百七十七万九千二百八十三美元有关的费用由于手部卫生违规。在手卫生遵守增长1.0％导致了每年可节省三九六五零美元到200张床位的医院。
结论：手卫生是不遵守是住院费用的增加的重要原因。在遵守最低限度的改善可导致大量节省住院费用。

lindahawk729

原文：
Hand Hygiene Noncompliance and the Cost of Hospital‐Acquired Methicillin‐Resistant Staphylococcus aureus Infection
Infect Control Hosp Epidemiol 2010;31:357–364
Background.Hand hygiene noncompliance is a major cause of nosocomial infection. Nosocomial infection cost data exist, but the effect of hand hygiene noncompliance is unknown.

Objective.To estimate methicillin‐resistant Staphylococcus aureus (MRSA)‐related cost of an incident of hand hygiene noncompliance by a healthcare worker during patient care.

Design.Two models were created to simulate sequential patient contacts by a hand hygiene–noncompliant healthcare worker. Model 1 involved encounters with patients of unknown MRSA status. Model 2 involved an encounter with an MRSA‐colonized patient followed by an encounter with a patient of unknown MRSA status. The probability of new MRSA infection for the second patient was calculated using published data. A simulation of 1 million noncompliant events was performed. Total costs of resulting infections were aggregated and amortized over all events.

Setting.Duke University Medical Center, a 750‐bed tertiary medical center in Durham, North Carolina.

Results.Model 1 was associated with 42 MRSA infections (infection rate, 0.0042%). Mean infection cost was $47,092 (95% confidence interval [CI], $26,040–$68,146); mean cost per noncompliant event was $1.98 (95% CI, $0.91–$3.04). Model 2 was associated with 980 MRSA infections (0.098%). Mean infection cost was $53,598 (95% CI, $50,098–$57,097); mean cost per noncompliant event was $52.53 (95% CI, $47.73–$57.32). A 200‐bed hospital incurs $1,779,283 in annual MRSA infection–related expenses attributable to hand hygiene noncompliance. A 1.0% increase in hand hygiene compliance resulted in annual savings of $39,650 to a 200‐bed hospital.

Conclusions.Hand hygiene noncompliance is associated with significant attributable hospital costs. Minimal improvements in compliance lead to substantial savings.

译文：
手卫生违规与MRSA医院感染的成本
医院感染控制与流行病学2010;31:357-364
背景：手卫生违规是医院感染的主要原因。医院感染成本数据的存在对于手卫生违规现象的影响尚属未知。
目标：估算医务人员护理病人过程中手卫生违规引发MRSA感染的成本。
设计：创建两个模拟手卫生违规的医务人员顺序接触病人的样本组。样本1组涉及与MRSA感染情况未知病人的医疗接触。样本2组涉及与MRSA定植病人接触后再与MRSA感染情况未知病人的医疗接触。第二个病人新发MRSA感染的概率使用正式公布的数据资料计算。共进行100万例手卫生违规模拟。感染引发的费用按总成本与例次成本统计。
环境：皇家大学医学中心，拥有750张床位的北卡罗来纳州达拉姆市三级医疗中心。 结果：样本1组共发生MRSA感染42例（感染率为0.0042%）。平均感染成本为$47,092（95%置信区间，$26,040–$68,146)；每次手卫生违规的平均成本为$1.98(95%置信区间, $0.91–$3.04)。样本2组共发生MRSA感染980例（感染率为0.098%）。平均感染成本为$53,598（95%置信区间，$50,098–$57,097)；每次手卫生违规的平均成本为$52.53(95%置信区间, $47.73–$57.32)。手卫生违规造成一间200张床位的医院每年MRSA感染所致支出$1,779,283。手卫生依从性每提高1%可为一间200张床位的医院每年节约$39,650。
结论：手卫生违规与于医院成本有着重大关联。极小的依从性改进可带来可观的节省（小小的依从性提高可大大节约医疗成本）。

过年

楼上两位翻译的真快，偶一定向你们学习，谢谢楼主提供材料

zhenkai

lindahawk729 译得不错 谢谢学习了

潮水

1.0% increase in hand hygiene compliance resulted in annual savings of $39,650 to a 200‐bed hospital
手卫生依从性每提高1%可为一间200张床位的医院每年节约$39,650。

hmjtzyy

手卫生依从性每提高1%可为一间200张床位的医院每年节约$39,650

清丽幽妙

"手卫生违规与于医院成本有着重大关联。极小的依从性改进可带来可观的节省"
为什么手卫生依从性还是比较低？值得感控者不断探索！

lwh1208

楼上的各位老师翻译的都不错，学习了！谢谢！

zjhlyf

4楼、5楼两位翻译的真快，偶一定向你们学习，谢谢楼主提供材料，很有一定的英语水准哦。