污染的奶瓶：新生儿ICU铜绿假单胞菌暴发感染的源头

David

American Journal of Infection Control
Volume 37, Issue 2, March 2009, Pages 150-154
Hemodynamic Monitoring in the Diagnosis and Management of Heart Failure

Major Article Contaminated feeding bottles: The source of an outbreak of Pseudomonas aeruginosa infections in a neonatal intensive care unit
污染的奶瓶：新生儿ICU铜绿假单胞菌暴发感染的源头

Carlos Sánchez-Carrillo PharmDa,

                               
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,

                               
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, Belén Padilla MDa, Mercedes Marín Phda, Marisa Rivera MDa, Emilia Cercenado PharmDa, Dolores Vigil MDb, Manuel Sánchez-Luna MDc and Emilio Bouza PhDa
aServicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario “Gregorio Marañón,” Madrid, Spain
bServicio de Medicina Preventiva, Hospital General Universitario “Gregorio Marañón,” Madrid, Spain
cServicio de Neonatología, Hospital General Universitario “Gregorio Marañón,” Madrid, Spain


Available online 6 December 2008.


BackgroundOutbreaks of Pseudomonas aeruginosa have been reported in relationship with contamination of staff fingernails, hands, water baths, hand lotions and others. To our knowledge, contamination of milk and feeding bottles as a source of an outbreak of P aeruginosa infections has not been reported. The incidence of P aeruginosa infection/colonization in our neonatal intensive care unit increased from 1.9 per 1000 patient-days in August 2004 to 8.8 per 1000 patient-days in September 2004.
MethodsSamples were collected including hand and body lotions, water from the incubator humidifying system, the health care worker hands, and the feeding bottle preparation room. Strains were epidemiologically characterized by pulsed-field gel electrophoresis of SpeI-digested genomic DNA. P aeruginosa was isolated from a total of 30 neonates during the period September 2004 to December 2004.
ResultsAll cultures (139) of hand and body lotions, water from the incubator humidifying system, and hands of health care personnel were negative. Nine out of 48 samples collected from the feeding bottle preparation room were positive for P aeruginosa (6 samples of in-house prepared milk and 3 samples of water from dishwashers). Pulsed-field gel electrophoresis with SpeI showed that the strains isolated from neonates and from environmental samples were identical. Discontinuation of in-house preparation of feeding bottles and incorporation of unidose milk bottles stopped the outbreak.
ConclusionThe preparation and solution of milk from multidose powder preparation may be a source of P aeruginosa infections in a neonatal intensive care unit. The use of manufactured, nonmanipulated, unidose feeding bottles should be considered more adequate.

David

merican Journal of Infection Control
Article in Press, Corrected Proof - Note to users
Contaminated feeding bottles: The source of an outbreak of Pseudomonas aeruginosa infections in a neonatal intensive care unit
被污染的奶瓶：新生儿重症监护室铜绿假单胞菌暴发感染源
Carlos Sánchez-Carrillo PharmDa, , , Belén Padilla MDa, Mercedes Marín Phda, Marisa Rivera MDa, Emilia Cercenado PharmDa, Dolores Vigil MDb, Manuel Sánchez-Luna MDc and Emilio Bouza PhDa
aFrom the Servicio de Microbiología Clínica y Enfermedades Infecciosas,
bServicio de Medicina Preventiva,
cServicio de Neonatología, Hospital General Universitario “Gregorio Marañón,” Madrid, Spain
Available online 6 December 2008.
Background
Outbreaks of Pseudomonas aeruginosa have been reported in relationship with contamination of staff fingernails, hands, water baths, hand lotions and others. To our knowledge, contamination of milk and feeding bottles as a source of an outbreak of P aeruginosa infections has not been reported. The incidence of P aeruginosa infection/colonization in our neonatal intensive care unit increased from 1.9 per 1000 patient-days in August 2004 to 8.8 per 1000 patient-days in September 2004.
Methods
Samples were collected including hand and body lotions, water from the incubator humidifying system, the health care worker hands, and the feeding bottle preparation room. Strains were epidemiologically characterized by pulsed-field gel electrophoresis of SpeI-digested genomic DNA. P aeruginosa was isolated from a total of 30 neonates during the period September 2004 to December 2004.
Results
All cultures (139) of hand and body lotions, water from the incubator humidifying system, and hands of health care personnel were negative. Nine out of 48 samples collected from the feeding bottle preparation room were positive for P aeruginosa (6 samples of in-house prepared milk and 3 samples of water from dishwashers). Pulsed-field gel electrophoresis with SpeI showed that the strains isolated from neonates and from environmental samples were identical. Discontinuation of in-house preparation of feeding bottles and incorporation of unidose milk bottles stopped the outbreak.
Conclusion
The preparation and solution of milk from multidose powder preparation may be a source of P aeruginosa infections in a neonatal intensive care unit. The use of manufactured, nonmanipulated, unidose feeding bottles should be considered more adequate.

David

emodynamic Monitoring in the Diagnosis and Management of Heart Failure
Major Article Contaminated feeding bottles: The source of an outbreak of Pseudomonas aeruginosa infections in a neonatal intensive care unit
污染的奶瓶：新生儿ICU铜绿假单胞菌暴发感染的源头
aServicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario “Gregorio Marañón,” Madrid, Spain
bServicio de Medicina Preventiva, Hospital General Universitario “Gregorio Marañón,” Madrid, Spain
cServicio de Neonatología, Hospital General Universitario “Gregorio Marañón,” Madrid, Spain
Available online 6 December 2008.
BackgroundOutbreaks of Pseudomonas aeruginosa have been reported in relationship with contamination of staff fingernails, hands, water baths, hand lotions and others. To our knowledge, contamination of milk and feeding bottles as a source of an outbreak of P aeruginosa infections has not been reported. The incidence of P aeruginosa infection/colonization in our neonatal intensive care unit increased from 1.9 per 1000 patient-days in August 2004 to 8.8 per 1000 patient-days in September 2004.
MethodsSamples were collected including hand and body lotions, water from the incubator humidifying system, the health care worker hands, and the feeding bottle preparation room. Strains were epidemiologically characterized by pulsed-field gel electrophoresis of SpeI-digested genomic DNA. P aeruginosa was isolated from a total of 30 neonates during the period September 2004 to December 2004.
ResultsAll cultures (139) of hand and body lotions, water from the incubator humidifying system, and hands of health care personnel were negative. Nine out of 48 samples collected from the feeding bottle preparation room were positive for P aeruginosa (6 samples of in-house prepared milk and 3 samples of water from dishwashers). Pulsed-field gel electrophoresis with SpeI showed that the strains isolated from neonates and from environmental samples were identical. Discontinuation of in-house preparation of feeding bottles and incorporation of unidose milk bottles stopped the outbreak.
ConclusionThe preparation and solution of milk from multidose powder preparation may be a source of P aeruginosa infections in a neonatal intensive care unit. The use of manufactured, nonmanipulated, unidose feeding bottles should be considered more adequate.

腊梅

不懂英文,所以不知其是怎么处理奶瓶的?我们都是用高压灭菌应该不会有问题吧.不过奶瓶的消毒要高度重视:lol