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Successive point prevalence surveys were conducted in November 2007 and 2008 to monitor
the prevalence of healthcare-associated infection (HCAI) in 13 grade III, 1st class hospitals in
Hubei Province of China, using the case definition criteria established by the Ministry of Health
in the People’s Republic of China. In total, of 20 350 patients surveyed, 833 (4.09%) HCAIs were
observed in 790 (3.88%) patients. There was no significant difference between the overall
prevalence of HCAI in 2007 (4.14%) and 2008 (3.72%). Respiratory tract infection was the most
common HCAI (63.15%), followed by surgical site infection (9.60%) and urinary tract infection
(8.64%). Only 35.29% (294/833) of HCAI patients had positive microbiology results. Gramnegative
bacteria were isolated most frequently and the most frequent organism was Pseudomonas
aeruginosa, followed by Escherichia coli, Acinetobacter baumannii and Staphylococcus
aureus. Antibiotic use was documented for 10 344 (50.83%) patients, and cephalosporins,
penicillins, and quinolones were the most commonly used agents for treatment or prophylaxis.
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