澳大利亚成功处置一起因医院建筑施工引起的血液病房曲霉菌暴发感染的经验

David

J Hosp Infect. 2008 Apr 2 [Epub ahead of print] Links
Successful control of an outbreak of invasive aspergillosis in a regional haematology unit during hospital construction works.
澳大利亚成功处置一起因医院建筑施工引起的血液病房曲霉菌暴发感染的经验
Chang CC, Cheng AC, Devitt B, Hughes AJ, Campbell P, Styles K, Low J, Athan E.
Department of Infectious Diseases, Geelong Hospital, Geelong, Victoria, Australia.

We report the successful control of an outbreak of six cases of nosocomial invasive aspergillosis (IA) in our haematology unit coinciding with major hospital construction works. Infection control changes included unit relocation, impermeable barriers at construction site, face-masking and voriconazole prophylaxis of 18 further high-risk patients, none of which developed breakthrough IA. A multi-faceted pre-emptive approach involving clinicians, hospital management, engineering and building departments is essential in preventing nosocomial IA outbreaks.

泉子

e used voriconazole as antifungal prophylaxisfor high-risk patients during the outbreak in viewof its activity against Aspergillus spp., its avail-ability in oral and intravenous formulation andease of dosing.
It is important also to recogniseen-vironmenta lfactors,reectedin the baselineinsti-tutional rate of IFI and modifying factors such asbuilding works.

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