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本帖最后由 老朽 于 2010-1-30 11:03 编辑
谁来翻译这个摘要?关于VAP的一个系统综述 译文有奖!
Journal of Hospital Infection (2007) 67, 1-8
《REVIEW Prevention of ventilator-associated pneumonia: analysis of studies published since 2004》
Summary As the most recent guidelines for the prevention of ventilatorassociated
pneumonia (VAP) were published four years ago, we have
conducted a systematic review to discover whether the recently published
articles should further influence existing guidelines. Articles published since
2004 dealing with infection control measures for prevention of VAP were
gathered and evaluated in order to identify evidence for the possible modification
of routine practice. Special emphasis was placed on randomized
controlled trials (RCTs), meta-analyses or systematic reviews and studies
applying multi-module interventions. A total of 15 RCTs and seven metaanalyses
or systematic reviews were found. In addition to these, five cohort
studies were identified where multi-module programmes were introduced
for reducing VAP rates. The data lead to the conclusion that topical use of
chlorhexidine for oral care is beneficial and subglottic secretion drainage
may lead to delayed onset of VAP. The remaining studies had only a minor
influence on existing guidelines for the prevention of VAP and confirmed
the earlier recommendations in several points. However, the studies investigating
multi-module programmes led to a substantial reduction of VAP of
between 31 and 57%. The data show that many VAP cases are preventable
and that there is room for improvement in many institutions. Often simple
interventions are useful for the reduction of VAP rates, for which the best
chances appeared to be the application of multi-module programmes. On
average a reduction of more than 40% seems to be possible. |