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家庭饮用水系统中衣原体和其他抗变形虫菌的流行率和多样性
自由生物变形虫在环境中是普遍存在的，特别是水。 在不利的生长条件（例如饥饿或干燥）的情况下，这些原生生物可以表现出抗性形式，称为孢囊。 囊肿结构帮助变形虫对抗各种消毒而得以生存。 因此，变形虫可以绕过饮用水处理厂中存在的所有屏障，并且可以到达水分配系统，在那里它们可以定植生物膜和沉积物。
这项工作首次报告了衣原体在饮用水中非常高的流行率和多样性，在48个被调查的家庭用水系统中，有35个（72.9％）中检测到。 且存在不同的军团菌和分枝杆菌，某些物种是已知人类感染病原体。
Title:
Prevalence and diversity of Chlamydiales and other amoeba-resisting bacteria in domestic drinking water systems DOI:
10.1016/j.nmni.2016.10.003 Abstract:
A growing number of human infections incriminate environmental bacteria that have evolved virulent mechanisms to resist amoebae and use them as a replicative niche. These bacteria are designated amoeba-resisting bacteria (ARB). Despite the isolation of these ARB in various human clinical samples, the possible source of infection remains undetermined in most cases. However, it is known that the ARB Legionella pneumophila, for instance, causes a respiratory infection in susceptible hosts after inhalation of contaminated water aerosols from various sources. The Chlamydiales order contains many ARB, such as Parachlamydia acanthamoebae or Simkania negevensis, previously implicated in human respiratory infections with no identified contamination sources. We thus investigated whether domestic water systems are a potential source of transmission of these Chlamydiales to humans by using amoebal culture and molecular methods. Other important ARB such as mycobacteria and Legionella were also investigated, as were their possible amoebal hosts. This work reports for the first time a very high prevalence and diversity of Chlamydiales in drinking water, being detected in 35 (72.9%) of 48 investigated domestic water systems, with members of the Parachlamydiaceae family being dominantly detected. Furthermore, various Legionella and mycobacteria species were also recovered, some species of which are known to be causal agents of human infections. All Authors:
J Lienard,A Croxatto,A Gervaix,Y Lévi,J-F Loret,K M Posfay-Barbe,G Greub First Authors:
Lienard J Correspondence:
Greub G
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发表于 2017-1-16 12:30
发表于 2017-1-16 13:43
