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当前微生态研究主要关注个体健康,本文从社会、伦理的角度论证其对公共健康的影响同样巨大。基于微生态研究的干预措施对群体肠道微生物的影响需要评估,本文提出“微生物监管责任”的概念及将改变微生物变成一项“公共卫生干预措施”的远期风险是未知的。微生物研究的转化还需要公众的认知信任与支持。
Title:
The Human Microbiome and Public Health: Social and Ethical Considerations DOI:
10.2105/AJPH.2015.302989 Abstract:
Rapid advances in human microbiome research point to an increasing range of health outcomes related to the composition of an individual's microbiome. To date, much research has focused on individual health, with a paucity of attention to public health implications. This is a critical oversight owing to the potentially shared nature of the human microbiome across communities and vertical and horizontal mechanisms for transferring microbiomes among humans. We explored some key ethical and social implications of human microbiome research for public health. We focused on (1) insights from microbiome research about damage to individual and shared microbiomes from prevalent societal practices, and (2) ethical and social implications of novel technologies developed on the basis of emerging microbiome science. All Authors:
Kieran C O’Doherty,Alice Hawkins Virani,Elizabeth Wilcox First Authors:
Kieran C O’Doherty Correspondence:
Kieran C O’Doherty
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