An Evidence-Based Catheter Bundle Alters Central Venous Catheter Strategy in New
本帖最后由 蓝鱼o_0 于 2012-9-3 16:52 编辑题目：An Evidence-Based Catheter Bundle Alters Central Venous Catheter Strategy in Newborn Infants
作者：Meggan Butler-O’Hara, RN, MSN, NNP1,2, Carl T. D’Angio, MD2,3, Hyacinth Hoey, RN, BSN2,
and Timothy P. Stevens, MD, MPH2,3
摘要：
Objective To assess whether introduction of an evidence-based percutaneously inserted central catheter (PICC)
care bundle reduced the risk of central line-associated bloodstream infection (CLABSI), thus altering the comparative
risk of CLABSI in infants.
Study design This retrospective cohort study included all infants for whom an umbilical venous catheter (UVC)
was placed as part of routine care between Jan 1, 2006, and Dec 31, 2009, a period during which standardized
PICC insertion and care bundles were introduced. Duration of UVC use was divided in #7 days and >7 days.
Results Infants in the #7 days UVC group had 1.0 CLABSI/1000 catheter days, and infants in the >7 days UVC
group had 4.0 CLABSI/1000 catheter days (P < .001). Controlling for birth weight, gestational age, and antibiotic
use, the >7 days UVC group had a greater risk of CLABSI (OR, 5.48) than the #7 days UVC group. CLABSI rate
increased more rapidly in UVC than PICC with increasing duration of catheter rose.
Conclusions Replacement of a UVC with a PICC when central venous access is needed after 7 days of age may
reduce CLABSI.
出处：(J Pediatr 2012;160:972-7).
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