JAC(2012年3月)：沙特阿拉伯王国非发酵菌耐药监测报告
J Antimicrob Chemother. 2012 Mar 29.Antimicrobial resistance among non-fermenting Gram-negative bacteria in Saudi Arabia.
Memish ZA, Shibl AM, Kambal AM, Ohaly YA, Ishaq A, Livermore DM.
SourcePreventive Medicine Directorate, Ministry of Health, Riyadh, Kingdom of Saudi Arabia.
Abstract
OBJECTIVES: Non-fermentative Gram-negative bacilli (non-fermenters) can cause serious healthcare-associated infections and are often resistant to multiple antibiotics. We examined resistance rates among these bacteria from different regions of Saudi Arabia.
METHODS: A cross-sectional study between January and December 2009 examined 8908 clinical non-fermenters from 24 hospitals across Saudi Arabia. Susceptibility testing was monitored to ensure compliance with CLSI guidelines, but the antibiotics tested were at the hospitals' discretion.
RESULTS: Out of the 8908 non-fermenters, most were Pseudomonas aeruginosa (72.9%), followed by Acinetobacter baumannii (25.3%) and Stenotrophomonas maltophilia (1.8%). Resistance rates among P. aeruginosa were: polymyxin B, 2.2%; imipenem, 15.9%; ciprofloxacin, 22.0%; amikacin, 22.9%; and gentamicin, 31.2%. Resistance rates among A. baumannii were: imipenem, 5.4%; polymyxin B, 13.2%; ciprofloxacin, 64.0%; trimethoprim/sulfamethoxazole, 73.8%; amikacin, 76.9%; and gentamicin, 77.8%. Resistance rates among S. maltophilia were: polymyxin B, 6.9%; trimethoprim/sulfamethoxazole, 20.5%; and ciprofloxacin, 38.9%. There was major variation in resistance rates between geographical regions.
CONCLUSIONS: Resistance rates among non-fermenters were high in Saudi Arabia and were variable among regions.
一篇并不复杂的耐药监测文章，却发表在JAC上，该期刊为SCI，2010年IF为4.659。
从中，我们可以学到什么？
版主真好学，第一次看到阿拉伯国家的文章。{:1_17:} 水平较高呦，很羡慕英语程度好的人，会员里藏龙卧虎哈。济南年会外语翻译的人选呐。
细菌耐药 发表于 2012-4-3 21:57 static/image/common/back.gif
一篇并不复杂的耐药监测文章，却发表在JAC上，该期刊为SCI，2010年IF为4.659。
从中，我们可以学到什么？ ...
来自欧美其他国家的耐药数据是大家都乐意看到的。
也非常期待中国的数据。
文章的技术难点很少，亮点有两个，样本量比较大，来自于24个医院，八千多的分离物。
我想我们的样本要远远超过他们。
蓝鱼o_0 发表于 2012-4-3 23:56 static/image/common/back.gif
来自欧美其他国家的耐药数据是大家都乐意看到的。
也非常期待中国的数据。
国家级耐药监测数据，我们是很难拿到，并写成论文的。如果有数据，写成SCI论文应该不难:) 细菌耐药 发表于 2012-4-4 09:52 static/image/common/back.gif
国家级耐药监测数据，我们是很难拿到，并写成论文的。如果有数据，写成SCI论文应该不难:)
国家级耐药监测数据我们无法获取，现在各省的临床检验中心要求二级以上医院进行耐药菌数据上报，是否考虑各中心按照区域定期反馈给单位多好的一件事！期待！
黑旋风 发表于 2012-4-4 10:11 static/image/common/back.gif
国家级耐药监测数据我们无法获取，现在各省的临床检验中心要求二级以上医院进行耐药菌数据上报，是否考虑 ...
是啊，要有一定的机制实现数据共享比较好。 国内的耐药数据一出手，就能把洋鬼子们吓跑一大群，可信度不高，发表可能很困难！
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