医疗机构环境中的诺如病毒
Norovirus in the hospital setting: virus introduction and spread within the hospital environmentJournal of Hospital Infection
Volume 77, Issue 2, February 2011, Pages 106-112
S. Mortera, G. Benneta, J. Fisha, J. Richardsa, D.J. Allenb, S. Nawazb, M. Iturriza-Gómarab, S. Brollyc and J. Grayc, ,
a Infection Prevention and Control Team, Norfolk and Norwich University Hospital, Norwich, UK
b Enteric Virus Unit, Virus Reference Department, Centre for Infections, Health Protection Agency, London, UK
c Specialist Virology Centre, Microbiology Laboratory, Norfolk and Norwich University Hospital, Norwich, UK
Received 20 September 2010;accepted 24 September 2010.Available online 16 December 2010.
Summary
Norovirus (NoV) strains were collected over a four-month period during 2009–2010 from hospitalised patients with symptoms of gastroenteritis. These were characterised in order to estimate how many strains were introduced into the hospital from the community. In addition, environmental swabbing was performed after clinical cleaning of bays or wards accommodating infected patients. This was performed in order to assess the efficiency of cleaning and identify any NoV contamination in the environment. A total of eight distinct genetic clusters of NoV GII-4 genotype were identified during the four-month period, with some wards experiencing multiple outbreaks with different GII-4 strains during the season. NoV was detected from 31.4% of environmental swabs post cleaning. Notes trolleys, computer keyboards, soap and alcohol dispensers, blood pressure equipment, pulse oximeters and tympanic thermometers were identified as NoV reservoirs but contamination was also found on surfaces around the bedside environment, and furniture, fixtures and fittings associated with toilets and shower rooms. The combination of detailed virus characterisation and environmental swabbing is a powerful tool for infection control audits to determine the size and scope of an outbreak and to monitor the efficiency of clinical cleaning.
Keywords: Environmental contamination; Genetic variants; Norovirus; Virus introduction 有中文版的就好了{:1_14:}{:1_17:} 回复 1# 潮水
潮水版主老师能提供中文版的吗？{:1_7:} 期待中文版的医疗机构环境中的诺如病毒，期待中。 请潮水版主老师能提供中文版的，谢谢！ 很遗憾，英文水平不高，阅读起来很费尽，可是此资料又很重要，放弃又适不得，希望能尽快提供中文版的，谢谢！ 在2009-2010年的4个月中，从有胃肠炎症状的住院病人中分离出诺如病毒株。本研究的特点是评价有多少病毒株从社区传到医院中，以及对感染病人居住过的病房或暂住处，在临床清洁后，进行环境采样，以此评价环境清洁的有效性，发现环境中诺如病毒的污染。在4个月中发现8个不同的基因簇的GII-4基因型诺如病毒，在此期间一些病房经历多次不同的GII-4病毒株爆发。在清洁后，31.4%的环境采样中发现诺如病毒。需要注意手推车、计算机键盘、皂液和酒精释放器、血压计设备、指脉仪和鼓膜温度计是诺如病毒的储存库，但在床旁环境中的物体表面、家具和与卫生间和浴室有关的固定器具和装饰也发现有污染。病毒鉴定结合环境采样是感染控制检查有力的工具，确定爆发的规模和范围，监测临床清洁的有效性。 回复 1# 潮水
病毒在环境中的采样谈何容易啊，几次诺如病毒感染暴发，环境中都没有做出来，老外这点真是厉害，要好好学习下
页:
[1]