研究发现：对进入ICU的患者进行MRSA的筛选能为医院节约成本（翻译在6楼4.20）
本帖最后由 婉若秋水 于 2011-4-20 10:14 编辑Screening patients in the intensive care unit (ICU) for methicillin-resistant Staphylococcus aureus (MRSA) produces cost savings for the whole hospital, according to a study that used a statistical simulation model published in the February issue of the American Journal of Infection Control, the official publication of APIC - the Association for Professionals in Infection Control and Epidemiolog.......
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回复 1# 桃子妖妖
一直很关注入住icu患者MRSA的筛查的事情。但是，涉及费用问题，很难作为常规进行。想请教桃子妖妖 版主，您院是怎样做的啊？ 回复 1# 桃子妖妖
我们也在关注MRSA的筛查工作，您是怎么做的？ 回复 1# 桃子妖妖
高手能给翻译一下吗？让更多的人可以学习。 耐药菌筛检也将是下一步感控人员面临的管理内容，医院在落实该项工作中将面临获益还是什么？该主题悬赏翻译中，翻译者将获得30金币，+1威望。
请英语棒棒的战友们来参与啊！ 本帖最后由 婉若秋水 于 2011-4-20 10:13 编辑
因时间有限，翻译中的错误请指正！谢谢！
（备注：第一个是低版本的，第二个是高版本的） 回复 6# Adler007
由于一次加分的限制，其他版主会补齐奖励金币。
辛苦了，期待你更多的精彩！ 美国很多州都立法强制筛检，但是目前筛检的方法，怎么做？谁来谈一谈，筛检的方法是否适合国情，所需费用和实际可操作性如何？ Adler007 发表于 2011-4-19 11:13 static/image/common/back.gif
因时间有限，翻译中的错误请指正！谢谢！
（备注：第一个是低版本的，第二个是高版本的）
Scandinavian Journal of Infectious Diseases, 2011; 43: 765–770
Is linezolid a risk factor for Gram-negative bacillus infections inintensive care unit patients? A comparative study with vancomycin
HOLGER STERZIK , ALEJANDRO SORIANO , AL-MONTASER MOHAMAD，JOS É ANTONIO MART Í NEZ , JAVIER FERNANDEZ , NAZARET COBOS ,LAURA MORATA & JOSEP MENSA
Abstract
Background: Linezolid is frequently used in critically ill patients with ventilator-associated pneumonia. Its potent activity against Gram-positive microorganisms and its high tissue penetration may favour Gram-negative colonization and infection.The aim of our study was to evaluate the risk for Gram-negative infections in critically ill patients treated with linezolid or vancomycin.
Methods: The cases of all patients admitted over an 18-month period to a hepatic intensive care unit for ≥1 week, and treated with linezolid or vancomycin, were retrospectively reviewed. The main clinical characteristics and infections due to Gram-negative bacteria in the month after starting linezolid or vancomycin were obtained.
Results: Seventy-one patients treated with linezolid and 68 treated with vancomycin fulfilled the inclusion criteria. Co-morbidities were similar in both groups. Patients on linezolid treatment had a longer stay in the ICU (mean±standard deviation 41± 38 days vs 18.4±13 days), received this treatment later (14.3±15.1 days vs 6.3±6.5 days), had a higher mean serum creatinine concentration (1.71±1.18 mg/dl vs 1.04 ±1.04 mg/dl), more often required haemodiafiltration (29.6% vs 13.2%), and 30 day-mortality was higher (42.3% vs 20.6%) than in patients receiving vancomycin. More than 95% in both groups received a broad-spectrum beta-lactam in addition to linezolid or vancomycin. The rate of Gram-negative infection during the following month was 28.2% in the linezolid group and 26.5% in the vancomycin group ( p > 0.5).
Conclusions: Linezolid was more frequently used in critically ill patients with longer ICU stay and renal failure. The rate of infection due to Gram-negative microorganisms was similar in patients who received linezolid or vancomycin.
谢谢，学习了，不过英文水平确实有限 筛检的方法 在国内收费能否执行? 谢谢，中英文对照，很容易看懂 对icu患者进行MRSA筛查，若收费，势必增加患者不满，若不收费，定会增加医院成本。， 筛查等的费用是个问题呵，有的医院直接算到患者身上，也觉得有些纠结呵。 下载学学，对于这个问题我们也很困惑。 下载学习了。。。。。。。。。。。。。。。。。。。。。 开始的时候很恍惚“发表于 2011-2-3 22:55 ”
是3年前的帖子啊，被人翻出来的，而且有翻译呢，Adler007老师太棒了
Adler007 版主老师发表于 2011-4-19 11:13 的翻译我粘出来了，炒炒旧饭，大家共同学习
Study Finds MRSA Screening Saves Hospitals Money
研究发现：筛选MRSA患者会节约医院钱
WASHINGTON--(BUSINESS WIRE)--Screening patients in the intensive care unit (ICU) for methicillin-resistant Staphylococcus aureus (MRSA) produces cost savings for the whole hospital, according to a study that used a statistical simulation model published in the February issue of the American Journal of Infection Control, the official publication of APIC - the Association for Professionals in Infection Control and Epidemiology.
二月份，美国--（华盛顿商业新闻社）--美国感染控制杂志，APIC （感染控制和流行病学专家联盟）官方出版社出版的关于筛选ICU内的MRSA患者会节约整个医院的成本的数学模型。
Conducted by a team of researchers at the Minneapolis Veterans Affairs Medical Center, a 279-bed teaching hospital and outpatient facility, the goal of the study was to determine the costs per hospital admission of screening ICU patients for MRSA and isolating patients who tested positive.
由明尼阿波利斯退伍军人医学中心的团队研究，其拥有279张床位的教学医院和门诊设施，研究的目标是要确定住进ICU的患者中每个筛选MRSA阳性的患者和单间患者所治疗所花费的金额之间的关系。
They found that even under the most conservative assumptions the screening would be cost-neutral if early detection of MRSA would lead to a reduced rate of infection and transmission within the hospital. Under optimal assumptions, screening could result in savings of almost $500 per hospital admission.
他们发现筛查最保守的假设也许是中立的：如果早期发现MRSA患者会减少医院内的感染率和传播率。最理想的假设，筛查会节约每个住院病人的500美元的费用。
The research was led by John A. Nyman, PhD, a health economist at the University of Minnesota School of Public Health.
该研究由美国明尼阿波利斯大学公共卫生学院的卫生经济学John A. Nyman,博士所带领。
It assessed the possible impact and cost effectiveness of active detection of MRSA and isolation on frequency of MRSA infections in the ICUs and hospital-wide.
该研究评估了有效检测MRSA与医院和ICU内频繁感染MRSA患者隔离的费用效益问题。
“This study presents evidence of the cost savings from implementing a program that targets the ICU population but that has an effect that is hospital-wide,” according to Dr. Nyman and his colleagues.
根据Nyman教授和他的团体：该项研究提供证据是关于目标ICU人数甚至是医院内执行一项措施会节约医疗成本。
“Although we find that this program pays for itself through the MRSA infections prevented, it is important that hospitals also consider how this type of program fits into their overall institutional, infection-prevention programs and realize that this intervention is only one of many alternative interventions that are designed to prevent healthcare-associated infections.”
虽然我们认为此项目的实施可以预防MRSA感染，这是很重要的,医院也考虑这种类型的项目符合他们感染预防的整体制度、程序和意识到这只是设计出来的预防MRSA感染的许多预防选择的措施之一。
The authors contend that this approach could complement other strategies to further reduce the incidence of MRSA infection. “We owe it to the patients to continue to assess and improve our preventive strategies,” they say in conclusion.
该作者说这种方法可以弥补其他策略,以进一步降低MRSA感染的发病率。他们说的结论是”我们应给予病人继续评估和提高的预防策略,”
MRSA is an antibiotic-resistant bacteria that can lead to severe infections and is associated with approximately 19,000 deaths annually, according to the Centers for Disease Control and Prevention (CDC).
根据疾病预防控制中心的数据，MRSA是一种耐抗生素的细菌，它能导致严重的感染和与每年19000死亡者相关联，
A 2006 survey conducted by APIC showed that 46 out of every 1,000 inpatients were either infected or colonized with MRSA -- a rate eight times higher than previous estimates. The annual cost to treat MRSA in hospitalized patients is estimated at $3.2 to 4.2 billion.
住院患者中感染MRSA者所花的年度费用被估计是3.2-4.2亿。
Some policy-makers have recommended universal screening to reduce hospital-acquired MRSA infection.
相关政策制定者应推荐普遍筛选会减少医院内获得性MRSA感染。
APIC has called for a more targeted, evidence-based approach that allows hospitals to tailor screening efforts based on their unique situation and recently published an updated Guide to the Elimination of MRSA Transmission in Hospital Settings, 2nd Edition, including a section on active surveillance testing.
APIC呼吁应更有针对性,循证的方式,使得医院基础筛选建立在特殊的情况和最近出版的一篇医院内消除MRSA传播消除指南之上。包括积极的筛选机制。
“The findings from this research by Dr. Nyman and colleagues are interesting but also highlight the importance of application of these by infection preventionists, based on risk assessment at their affiliated facilities,” said APIC 2011 President Russell Olmsted, MPH, CIC, Epidemiologist in Infection Prevention & Control Services, St. Joseph Mercy Health System, Ann Arbor, Michigan.
APIC 2011年CIC 流行病学感染预防控制志愿者，St. Joseph Mercy健康系统Ann Arbor, Michigan. Russell Olmsted博士说“从Dr. Nyman 及团队的研究发现是有意义的，但是也考虑为了预防感染所付出的过高的成本，基于所有设施设备中风险因素考虑”
“A broad focus that addresses prevention of all pathogens is critical. With the U.S. government’s increased focus on preventing all HAIs, it will be even more important for facilities to make sure they are doing everything possible to reduce and ultimately eliminate these infections.”
一个更广泛的关注点是关于所有诊疗措施都是有风险的。美国政府更加关注预防医院感染事件。更重要的是政府应给医院提供设施确保医院减少和消除医院感染。
(AJIC 2011; 39 )
Full text of the article is available to journalists upon request; contact Liz Garman, APIC, 202-454-2604, egarman@apic.org to obtain copies.
这篇文章是经新闻记者调查获得的，Liz Garman, APIC, 202-454-2604, 202-454-2604。通过 egarman@apic.org 获得副本。
ABOUT AJIC: AMERICAN JOURNAL OF INFECTION CONTROL
AJIC: American Journal of Infection Control (www.ajicjournal.org) covers key topics and issues in infection control and epidemiology.
AJIC:美国感染控制杂志（www.ajicjournal.org）包含感染控制和流行病学方面的关键性的论点和事件。
Infection preventionists, including physicians, nurses, and epidemiologists, rely on AJIC for peer-reviewed articles covering clinical topics as well as original research. 感染预防者包括内科医师、护士和流行病学专家，AJIC杂志依靠纯研究者关于临床研究者
As the official publication of APIC - the Association for Professionals in Infection Control and Epidemiology - AJIC is the foremost resource on infection control, epidemiology, infectious diseases, quality management, occupational health, and disease prevention. AJIC also publishes infection control guidelines from APIC and the CDC. Published by Elsevier, AJIC is included in MEDLINE and CINAHL.
ABOUT APIC
APIC’s mission is to improve health and patient safety by reducing risks of infection and other adverse outcomes. The association’s more than 14,000 members direct infection prevention programs that save lives and improve the bottom line for hospitals and other healthcare facilities around the globe. APIC advances its mission through education, research, collaboration, practice guidance, public policy and credentialing. Visit APIC online at www.apic.org. For consumer-related information, visit www.preventinfection.org.
APIC的使命是提高健康和病人安全通过减少风险相关感染和不利的支出。该协会有1400多参与者的感染预防项目是挽救生命和提高全球范围内医院和其他健康服务中心的底线，APIC提出了任务就是通过教育、研究u、合作、操作指南、公共政策和政策，APIC访问者可以登录www.apic.org.，获得先关信息可以登录www.preventinfection.org.
NOTES FOR EDITORS
“Cost of screening intensive care unit patients for methicillin-resistant Staphylococcus aureus in hospitals,” appears in the American Journal of Infection Control, Volume 39, Issue 1 (February 2011).
Authors:
John A. Nyman, PhD, Division of Health Policy and Management, University of Minnesota School of Public Health, Minneapolis, MN
Christine H. Lees, MPH, RN, Infectious Disease Epidemiology, Prevention & Control Division, Minnesota Department of Health, St. Paul, MN
Lindsay A. Bockstedt, PhD, Division of Health Policy and Management, University of Minnesota School of Public Health, Minneapolis, MN
Gregory A. Filice, MD, Infectious Disease Section, Veterans Affairs Medical Center, Minneapolis, MN; and Division of Infectious Diseases, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN
Catherine Lexau, PhD, MPH, Infectious Disease Epidemiology, Prevention & Control Division, Minnesota Department of Health, St. Paul, MN
Lindsey J. Lesher, MPH, Infectious Disease Epidemiology, Prevention & Control Division, Minnesota Department of Health, St. Paul, MN
Kathryn Como-Sabetti, MPH, Infectious Disease Epidemiology, Prevention & Control Division, Minnesota Department of Health, St. Paul, MN
Ruth Lynfield, MD, Infectious Disease Epidemiology, Prevention & Control Division, Minnesota Department of Health, St. Paul, MN
Corresponding Author: John A. Nyman, PhD, Division of Health Policy and Management, School of Public Health, University of Minnesota. 正想做多重耐药菌的主动筛查，这个可以派上用场，谢谢。 下载学学，对于这个问题我们也很困惑。 {:1_17:}下载学习了.....
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