静脉注射液污染引起的菌血症
本帖最后由 潮水 于 2010-4-5 15:33 编辑Contamination of intravenous fluids: A continuing cause of hospital bacteremia
American Journal of Infection Control
Volume 38, Issue 3, Pages 217-221 (April 2010)
Background
Nosocomial bacteremia caused by the contamination of intravenous (IV) infusates is considered rare. Unfortunately, this problem has been underestimated because its identification requires culturing infusates, a procedure not performed routinely.
Methods
This study was conducted in a referral hospital where IV infusates are admixed in nursing areas. The aim was to determine the prevalence of infusate contamination in adult patients with gram-negative rod (GNR) bacteremia. Over a period of 32 months, a specimen of infusate was drawn for culture from each patient recruited after the laboratory reported a GNR in the blood.
Results
A total of 384 infusates were cultured from 384 patients who had been diagnosed with GNR bacteremia. Seven infusates grew a GNR in culture, for a contamination rate of 2% (7/384; 95% confidence interval = 1% to 3%). In all cases, the infectious organism was the same as the organism isolated from the blood. Infusate contamination was responsible for 7% (7/108; 95% CI = 2% to 11%) of all primary bloodstream infections and 11% (7/62; 95% CI = 2% to 22%) of all primary bloodstream infections not associated with central venous catheter infection.
Conclusions
For patients in hospitals where IV drugs are admixed in nursing units, we recommend instituting infusate culture as routine practice following the diagnosis of a GNR in the blood.
Key Words: Bloodstream infection, catheter-related infection, health care quality, hospital infection, infusions, intravenous 静脉注射液引起的菌血症很少被关注,静脉注射液的革兰氏阴性菌的污染率是2%。 哥哥,需要翻译吗?有分挣吗? 回复 3# nancywhite
欢迎参加翻译! 背景:很少考虑静脉注射infusates(个人认为可能是指冲配好的补液)污染造成的院内菌血症。不幸的是,问题一直被低估,因为发现这种情况需要对infusates进行培养,这种方法没有常规使用。
方法:本研究在一家转送医院进行,其静脉infusates在护士工作区域内进行冲配。目标是确定在有革兰氏阴性杆菌菌血症的成人病人中infusates污染的流行程度。在经过32个月,实验室血培养中报告革兰氏阴性杆菌后,每一个感染病人采取infusates标本。
结果:从384个诊断为革兰氏阴性菌血症的患者中采取384个infusates标本,7个标本培养出革兰氏阴性杆菌,污染率是2%(7/384; 95% 可信区间 = 1% to 3%)。在所有病例中,感染性有机物与血中分离的有机物一样多。Infusates污染占所有原发性血流感染的7% (7/108; 95% CI = 2% to 11%),占所有不伴有中心静脉导管感染的原发性血流感染的11%(7/62; 95% CI = 2% to 22%)。
结论:对于住院病人,静脉使用药物在护士单元配置,我们推荐在诊断血流中有革兰氏阴性杆菌后常规进行infusates培养。 回复 5# gemao
感染性有机物与血中分离的有机物一样多。什么意思,能帮我们再解释一下吗? 应该是:感染性有机物与血培养中分离的有机物一样(相同)。
不好意思,多打一个字。 回复 6# 缭绕
In all cases, the infectious organism was the same as the organism isolated from the blood.
静脉注射液中的病原菌与病人血液中分离的病原菌相同。 infectious organism 引起感染的病原体 查到原文
gjs661 发表于 2012-7-10 20:26 static/image/common/back.gif
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