泛耐药结核,我们是接受教训?还是重复历史?

潮水

Tilte: Extensively drug-resistant tuberculosis: are we learning from history or repeating it?

Author: Dukes Hamilton C, Sterling TR, Blumberg HM, Leonard M, McAuley J, Schlossberg D, Stout J, Huitt G.

Sourse: Clin Infect Dis. 2007 Aug 1;45(3):338-42. Epub 2007 Jun 22.

Tuberculosis (T is an enormous global public health problem. Cases of extensively drug-resistant TB (XDR-T are being reported in increasing numbers across the globe. A large outbreak of XDR-TB associated with rapid and nearly universal mortality has been reported among patients with human immunodeficiency virus infection or acquired immunodeficiency disease in South Africa who have been receiving standard TB therapy and antiretrovirals. Epidemiologic features of this outbreak make it highly suspicious for health care-associated transmission. We urge the Infectious Diseases Society of America and its members to increase involvement in ongoing international TB prevention and treatment efforts and to develop a registry of experts in infection control and laboratory and disease management. We urge advocacy for increased funding for domestic and global TB control programs, including expanded access to sputum culture and drug susceptibility testing, as well as funding for TB clinical trials and research capacity. We believe that substandard TB diagnostic tests are not acceptable for TB control in resource-poor countries. We urge the development of shorter, less toxic TB treatment and prevention regimens. Funding of TB control and research should be reassessed to prevent budget cuts at a time when the disease is killing as many as 2 million people a year.
题目: 泛耐药结核,我们接受教训?还是重复历史?

作者: Dukes Hamilton C, Sterling TR, Blumberg HM, Leonard M, McAuley J, Schlossberg D, Stout J, Huitt G

来源: Clin Infect Dis. 2007 Aug 1;45(3):338-42. Epub 2007 Jun 22

肺结核(TB )是一项全球范围内的重大公共卫生问题.报道显示泛耐药结核(XDR-TB )全球范围内都在不断增加.
在南非的一次泛耐药结核大爆发中,一些人类免疫缺陷病毒(HIV)感染及获得性免疫缺陷综合征(AIDS)的病人被泛耐药结核菌感染,即便是接受了规范的抗结核及抗逆转录病毒的治疗,这些病人依然在很短的时间内就几乎全部死亡了.这次大爆发的流行病学特征让卫生保健变得无法再被信任了.

我们呼吁美国感染疾病协会的成员们更多地倾力于目前的全球结核防治工作,完善感染控制,实验室及疾病管理方面的专家注册和登记;增加国内及全球结核防控项目的资金投入,加强痰传播途径管理,药物敏感性监测,以及结核病的临床研究能力,在欠发达国家不合标准的结核诊断检测同样无法接受,而应代之以疗程短,毒副作用小的治疗和防控措施.目前,结核病的控制和研究基金还需要重新评估,以避免削减预算的可能,毕竟这还是个每年会夺去200万人生命的疾病.（摘自丁香园）

[ 本帖最后由 潮水 于 2007-11-4 21:28 编辑 ]

楚楚

学习啦！:handshake :handshake

星火

竟这还是个每年会夺去200万人生命的疾病.:'(
泛耐药结核,我们是接受教训?还是重复历史?:L :L
一个紧迫的全球范围内的重大公共卫生问题!!不仅仅是接受教训,更重要是培训和教育,普及预防控制泛耐药结核的理论和知识,加强痰传播途径管理,药物敏感性监测,提高及时正确诊断和规范化治疗率!!加强报告和疫情管理,形成强大的网络系统.或许会有效?!:liumangtu

楚楚

落实结核病转诊制度十分必要，但实际上免费治疗肺结核政策惠及的人群非常有限。

潮水

意！说是免费，覆盖面很有限！

莲雾

非泛耐药结核大爆发是个教训，但汲取教训的人还不多。:Q

柳莹依

结核还是归口管理，规范治疗。

绿叶

悲啊,我们医院的大夫为了完成自己的经济效益,对肺结核病人就是不转诊.还说我是吃里爬外,工作难搞啊 [/quote]
应该将这种情况告知院领导,传染病管理可是不能有半点马虎,如院长不管,不久他就会丢乌纱帽了!