DYEY范特西 发表于 2023-9-12 13:17

【文献】抗生素管理对多重耐药菌及艰难梭菌定植率与感染率的影响

   
      多重耐药菌及艰难梭菌对于人类健康的威胁成为了世界公共卫生领域共同关注的焦点,随着WHO及我国对于抗菌药物管理遏制细菌耐药相关指南、文件的颁布,越来越多的感染控制领域学者团队致力于多重耐药细菌、真菌的防控策略。      艰难梭菌是一种厌氧生长的革兰阳性梭状产毒芽孢杆菌,为人类肠道中的正常菌群,抗生素的应用可导致该菌过度生长,与伪膜性肠炎(pseudomenbranous colitis,PMC)及抗生素相关性腹泻(antibiotic-associated diarrhoea)关系密切。目前认为25%的抗生素相关性腹泻由艰难梭菌引发。随着广谱抗菌药物的广泛使用,在全球范围内,艰难梭菌相关性腹泻发生率不断升高,近年来出现暴发流行,其流行菌株发生基因变异,产生毒素的能力增加,患者病死率及病情复发率升高,已引起医学界的重视。      今天分享一篇2017年发表于《LANCET INFECT DIS》:抗生素管理对多重耐药菌及艰难梭菌定植率与感染率的影响-一项系统综述和meta分析
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


背景:抗生素管理方案已被证明可以减少抗生素的使用和医院相关费用,我们目的是评估抗生素管理对多重耐药菌及艰难梭菌感染率和定植率的影响。方法:对于这项系统综述和meta分析,我们检索了PubMed、Cochrane等系统综述数据库,包括从1960年1月1日至2016年5月31日,在Web of Science上发表的研究中,分析了抗生素管理方案对住院患者感染率、抗生素耐药菌定植率和艰难梭菌感染率的影响。两位作者独立评估试验的合格性并提取数据,涉及长期护理机构的研究排除在外。主要结果是在实施抗生素管理前后每1000个患者日的目标感染和定植的发病率(IRs),在实施抗生素管理之前和之后使用随机效应模型进行Meta分析异质性。结果:我们在Meta分析中纳入了32项研究,包括9056241个患者日和159个IRs估计值。抗生素管理方案降低了MDR革兰氏阴性杆菌定植率和感染发生率(减少51%;IR 0.49,95%CI 0.35-0.68;p<0.0001)、产超广谱β-内酰胺酶革兰氏阴性菌(48%;0.52,0.27-0.98;p=0.428)耐甲氧西林金黄色葡萄球菌(37%;0.63,0.45-0.88;p=0.0065)以及艰难梭菌(32%;0.68,0.53-0.88;p=0.0029)。与单独实施时相比,当抗生素管理方案与感染控制措施一起实施时更有效(IR 0.69,0.54-0.88;p=0.030),尤其是手卫生干预(IR 0.34,0.21–0.54;p<0.0001)。对于耐万古霉素肠球菌(VRE)、喹诺酮耐药和氨基糖苷耐药革兰氏阴性菌的IRs抗生素管理没有效果。

木木叶落87 发表于 2023-9-12 13:51

一直期待有一个版块能够进行文献的专场分享。

DYEY范特西 发表于 2023-9-12 13:52

木木叶落87 发表于 2023-9-12 13:51
一直期待有一个版块能够进行文献的专场分享。

我们一起努力吧 ~

缭绕 发表于 2023-9-12 13:59

能具体分享一下进行了哪些抗生素管理?比如是不是轮换用药?或者是停用某种三代头孢?还是我国现在推行的三级审批制?

缭绕 发表于 2023-9-12 14:01

木木叶落87 发表于 2023-9-12 13:51
一直期待有一个版块能够进行文献的专场分享。

论坛有个《文献、论文、科研、基金》板块。我也有此意,我们现在很多新版主的学历都很高,可以指导大家如何进行文献阅读

DYEY范特西 发表于 2023-9-12 14:06

缭绕 发表于 2023-9-12 13:59
能具体分享一下进行了哪些抗生素管理?比如是不是轮换用药?或者是停用某种三代头孢?还是我国现在推行的三 ...

缭绕老师,我怕过于冗长就进行了精简。

简单来说这是一篇我们非常熟悉的分析方法:META分析。
作者检索了PubMed, Cochrane系统综述数据库等,搜索时间从1960年1月1日至2016年5月31日。关键词是“抗生素和管理”或者"抗生素,干预和耐药性"以及“甲氧西林或革兰氏阴性菌”或“大肠杆菌”或“艰难梭菌”或“ESBL”或“产超广谱β-内酰胺酶”或“假单胞菌”或“不动杆菌”或“万古霉素”或“肠球菌”

最后有32项研究被纳入,这些研究是在20个国家中在1992年和2014年之间做的,代表人数最多的国家分别是美国(5项研究)、日本(4项研究)和德国和法国(各3项研究)。最常见的研究设计是前后对照研究(17 研究),队列研究(7研究)和中断时间序列研究(6研究)。大约50%的干预是在整个医院中做的(15研究),而17项(53%)研究干预措施集中在特定的病房,例如ICU等。

最常见的抗生素管理干预措施是督导质控模式和限制性政策实施。在10项(31%)研究中,抗生素管理方案是与感染控制措施共同实施的,最常见的是手卫生和患者筛查。21项(66%)研究评估了仅针对感染的抗生素管理方案。

最后的结果如文中所示,G-MDRO细菌显著降低。
更多的是利用循证的方法证明,对于抗菌药物进行干预管理对多耐降低是有较高证据的

缭绕 发表于 2023-9-12 14:10

DYEY范特西 发表于 2023-9-12 14:06
缭绕老师,我怕过于冗长就进行了精简。

简单来说这是一篇我们非常熟悉的分析方法:META分析。


最常见的抗生素管理干预措施是督导质控模式和限制性政策实施

{:1_28:}怎么感觉似曾相识呢!这些我们国内都是这么做的,为什么耐药菌反而越来越多呢!

DYEY范特西 发表于 2023-9-12 14:43

缭绕 发表于 2023-9-12 14:10
怎么感觉似曾相识呢!这些我们国内都是这么做的,为什么耐药菌反而越来越多呢! ...

这是一个让人深思的好问题;个人直言不讳,国情不一样人口基数不一样,我国的抗菌药物管理还有很长的一步路要走~包括居民大众对于抗菌药物的普及意识。

举个例子,最早的时候泌尿系感染可能认为是一种相对简单的感染,有多少人自行去药房购买环丙沙星、左氧氟沙星等喹诺酮类药物,吃个几天就自己停了,然后再次感染的时候加码使用碳青霉烯类药物,如此往复造成治疗的困难。

不做永远是0,做了可能是跬步。都说感控工作是需要情怀的~~~

jerkran 发表于 2023-9-12 16:01

缭绕 发表于 2023-9-12 14:10
怎么感觉似曾相识呢!这些我们国内都是这么做的,为什么耐药菌反而越来越多呢! ...

因为国内卫生这条线落实是问题,数据也假,,何况抗菌药物管理不只是医院这条线的事,是全社会的事

jerkran 发表于 2023-9-12 17:03

The landlord does not post the original text, can you post the DOI number down, like Zheng Yi evidence-based infection control {:1_12:}{:1_12:}{:1_12:}

DYEY范特西 发表于 2023-9-12 21:58

jerkran 发表于 2023-9-12 17:03
The landlord does not post the original text, can you post the DOI number down, like Zheng Yi eviden ...

OK,Sir I will

10.1016/S1473-3099(17)30325-0

jerkran 发表于 2023-9-13 16:40

DYEY范特西 发表于 2023-9-12 21:58
OK,Sir I will

10.1016/S1473-3099(17)30325-0

Thank you, sir            {:1_12:}{:1_12:}{:1_12:}
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查看完整版本: 【文献】抗生素管理对多重耐药菌及艰难梭菌定植率与感染率的影响