多重耐药定植
请问各位老师，多重耐药菌为定植菌，什么时候解除隔离啊？。。。。。。。。。。。。 按照解除隔离的标准 2021年《临床重要耐药菌感染传播防控策略专家共识 》３.3.3 隔离期限 原则上应隔离至耐药菌培养连续两次阴性。对于部分长期携带耐药菌患者，可以至疾病症状消失出院时。
《WS/T 826—2023碳青霉稀类药肠杆菌预防与控制标准》
6.3.6 碳青霉烯类耐药肠杆菌感染或定植患者宜隔离至出院。
6.3.7 若患者长期住院，应连续两次采样阴性，且采样时间相隔 24h 或以上，可解除隔离。 目前临床上应用的情况是，连续两次培养不是多耐，就可解除隔离。 好像是没有明确的要求的，这个是美国CDC相关的答复：
There is currently not enough information for CDC to make a general recommendation on when isolation can be discontinued for patients colonized or infected with CRE. CRE colonization can be prolonged (> 6 months). Across multiple studies, predictors of prolonged CRE carriage have been found to include:
exposure to antibiotics
presence of an invasive device
higher Charlson’s co-morbidity scores
number of hospital admissions
admission from another facility
admission from or discharge to a long-term care facility
Presence of these predictors should be considered when deciding whether to discontinue Contact Precautions.
If considering discontinuing Contact Precautions based on the results of surveillance cultures, it is appropriate to wait for at least 3 to 6 months since last positive culture or screen.The decision to discontinue Contact Precautions for an individual with a history of colonization or infection with CRE should be made in consultation with public health. In general, failure to identify CRE from at least two sets of screening cultures are the minimum criteria that should be met before an episode of colonization is considered resolved. Additionally, retesting of the site(s) that were positive initially from clinical cultures is usually indicated, particularly non-sterile sites such as a wound or urine. 学习了，谢谢老师们解答 我们定植的一般隔离到出院 去定植治疗后，连续两次培养阴性可以解除隔离 我们医院，也是定植的一般隔离到出院 定植的一般隔离到出院
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