David 发表于 2007-9-27 12:19

警惕多重耐药鲍曼在全球的扩散——10月份的AAC专题minireview

/kl[ilg Global Challenge of Multidrug-Resistant Acinetobacter baumannii

Federico Perez,1 Andrea M. Hujer,2 Kristine M. Hujer,2 Brooke K. Decker,3 Philip N. Rather,4 and Robert A. Bonomo2,3*
Division of Infectious Diseases and HIV Medicine, University Hospitals, Case Medical Center,1 Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center,2 Case Western Reserve University School of Medicine, Cleveland, Ohio,3 Emory University, Atlanta, Georgia4

We may soon be facing the end of the "antibiotic era." The initial and seemingly unstoppable success of antibiotics, the fruit of human ingenuity, has been countered by an escalation of resistance mechanisms in bacteria. This crisis has been described as an "unwinnable war" (www.wellcome.org). The statistics compiled as a result of surveillance efforts illustrate the emergence of many genera of bacteria that are resistant to all antibiotics (57, 60). The genus Acinetobacter epitomizes this trend and deserves close attention. Acinetobacter spp. display mechanisms of resistance to all existing antibiotic classes as well as a prodigious capacity to acquire new determinants of resistance (7). The increasing recovery in the clinic of multidrug-resistant (MDR) Acinetobacter baumannii is a frightening reality (112). This review summarizes the worldwide emergence of antibiotic-resistant A. baumannii as a nosocomial pathogen and focuses on its mechanisms of resistance against selected antibiotics. It concludes with a summary of current strategies in the treatment of MDR A. baumannii and offers perspectives on the control of this global public health threat.

缭绕 发表于 2007-9-27 12:29

回复 #1 David 的帖子

多耐药鲍氏是我们国内多还是国际性的？反正我们这儿是司空见惯了:lol :lol

David 发表于 2007-9-27 12:40

不得不承认国内真的很多，威尔士医院做全耐药鲍曼的研究，可是就是找不到这样的细菌，搞笑来，后来还是从国内转了几株送给他们，胸闷:L

缭绕 发表于 2007-9-27 13:00

回复 #3 David 的帖子

真奇怪啊！我院ICU最初是铜绿，后来出现了全耐的鲍氏，科主任无奈地说：是XXX带进来的！哎，看来威尔士医院还是一片净土啊！可千万要注意生物安全啊！

星火 发表于 2007-9-27 13:05

回复 #4 缭绕 的帖子

在ICU鲍曼排在前几位,已经引起我们关注,不过全耐的尚未发现.

gaoxd5 发表于 2007-9-27 14:58

看来zhangfh 版那里还是一片净土，上海部分医院的统计数字，鲍曼对泰能的耐药率已经高达40%，实在是可怕！！

星火 发表于 2007-9-27 15:24

回复 #6 gaoxd5 的帖子

:funk: 也不能说全无?或许没有检测出

David 发表于 2008-3-27 15:11

回复 #7 zhangfh 的帖子

这个问题更麻烦

David 发表于 2008-3-27 15:11

回复 #7 zhangfh 的帖子

这个问题更麻烦

星火 发表于 2008-3-27 21:06

回复 #9 David 的帖子

今天在ICU见到一例全耐的鲍曼:L 不知道如何控制??
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