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Effect of low-concentration chlorine dioxide gas against bacteria and viruses on a glass surface in wet environments.作者:
Morino H,Fukuda T,Miura T,Shibata T
1Research and Development Department, Taiko Pharmaceutical Co., Ltd, Suita, Osaka, Japan.
Aims: To evaluate the efficacy of low-concentration chlorine dioxide (ClO(2) ) gas against model microbes in the wet state on a glass surface. Methods and Results: We set up a test room (39 m(3) ) and the ClO(2) gas was produced by a ClO(2) gas generator that continuously releases a constant low-concentration ClO(2) gas. Influenza A virus (Flu-A), feline calicivirus (FCV), Staphylococcus aureus and Escherichia coli were chosen as the model microbes. The low-concentration ClO(2) gas (mean 0·05 ppmv, 0·14 mg m(-3) ) inactivated Flu-A and E. coli (>5 log(10) reductions) and FCV and S. aureus (>2 log(10) reductions) in the wet state on glass dishes within 5 h. Conclusions: The treatment of wet environments in the presence of human activity such as kitchens and bathrooms with thelow-concentration ClO(2) gas would be useful for reducing the risk of infection by bacteria and viruses residing on the environmental hard surfaces without adverse effects. Significance and Impact of the Study: This study demonstrates that the low-concentration ClO(2) gas (mean 0·05 ppmv) inactivates various kinds of microbes such as Gram-positive and Gram-negative bacteria, enveloped and nonenveloped viruses in the wet state.
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目的:评价低浓度二氧化氯(ClO(2)气体对玻璃表面湿态模型微生物的杀灭效果。
方法与结果:我们设置了一个试验室(39m(3),用连续释放低浓度ClO(2)气体的ClO(2)气体发生器产生ClO(2)气体。以甲型流感病毒(Flu-A)、猫杯状病毒(FCV)、金黄色葡萄球菌和大肠杆菌为模型菌。低浓度ClO(2)气体(平均0.05ppmv,0.14mg m(-3))在5h内使甲型流感病毒和大肠杆菌(>5log(10)还原)以及FCV和金黄色葡萄球菌(>2log(10)还原)在玻璃盘湿态下灭活。因为具有低浓度ClO(2)气体的厨房和浴室将有助于减少细菌和病毒在环境坚硬表面上的感染风险,而不会产生不利影响。
本研究的意义和影响:本研究表明低浓度ClO(2)气体(平均0.05ppmv)对湿态下革兰氏阳性菌和革兰氏阴性菌、包膜病毒和非包膜病毒等各种微生物均有灭活作用。
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