欧洲四国ICU导管相关血流感染的流行病学，医学特征和花费：基于文献和数据的估计
Journal of Hospital InfectionVolume 72, Issue 2, June 2009, Pages 97-103
Review Epidemiology, medical outcomes and costs of catheter-related bloodstream infections in intensive care units of four European countries: literature- and registry-based estimates
欧洲四个国家的ICU导管相关血流感染的流行病学，医学特征和花费：基于文献和数据的估计
E. Tacconellia, G. Smithb, K. Hiekec, A. Lafumad, http://www.sciencedirect.com/scidirimg/entities/REcor.gif, http://www.sciencedirect.com/scidirimg/entities/REemail.gif and P. Bastidee
aDepartment of Infectious Diseases, Catholic University, Rome, Italy
bDepartment of Microbiology, Royal Liverpool Hospital, Liverpool, UK
cNeosHealth, Binningen, Switzerland
dCemka Eval, Bourg-la-Reine, France
eJohnson&Johnson Wound Management (a division of Ethicon), Issy-Les-Moulineaux, France
Received 5 November 2008;
accepted 18 December 2008.
Available online 25 February 2009.
SummaryDespite high incidence rates, little information is available on the burden of illness of catheter-related bloodstream infections (CRBSIs) in Europe. A review of the available data was performed to estimate the clinical outcomes and costs associated with CRBSIs during intensive care unit (ICU) stays in four European countries (France, Germany, Italy and the UK). Based on these data we have estimated the CRBSI-related mortality and the annual costs associated with CRBSIs in the aforementioned countries. Results show large variation between countries: 1.12–4.2 CRBSI per 1000 catheter days, 8400–14 400 CRBSIs episodes per year, 1000–1584 deaths per year, 15 960–201 600 ICU days caused by CRBSIs and
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