2014年全国耐药网监测数据
本帖最后由 乔-乔 于 2015-2-7 12:38 编辑首先感谢楼主分享2014年全国耐药监测网数据{:1_17:}不过,这份资料中关于药敏选择的抗菌药物有诸多的错误,请SIFIC同道找出有哪些错误!慧眼识错,回帖有加分哦 !
全国细菌分布时间:2014年第1季度-2014年第4季度
细菌中文名称细菌英文名称菌株数量占比
其他330520.83%
大肠埃希菌Escherichia coli300018.90%
肺炎克雷伯菌Klebsiella pneumoniae235514.84%
铜绿假单胞菌Pseudomonas aeruginosa197912.47%
鲍曼不动杆菌Acinetobacter baumannii170910.77%
Staphylococcus aureus ss. aureusStaphylococcus aureus ss. aureus12057.59%
肺炎链球菌Streptococcus pneumoniae7604.79%
Staphylococcus albusStaphylococcus albus4512.84%
白色念珠菌Candida albicans4042.55%
阴沟肠杆菌阴沟亚种Enterobacter cloacae3602.27%
屎肠球菌Enterococcus faecium3412.15%
15869100%
全国鲍曼不动杆菌耐药性统计时间:2014年第1季度-2014年第4季度
药品株数S%I%R%NS%?%
阿莫西林/克拉维酸6297.5%1.9%90.6%0.0%0.0%
氨曲南10771.0%0.6%98.1%0.0%0.2%
头孢唑啉8750.3%0.0%99.4%0.0%0.2%
头孢吡肟167216.6%1.7%81.8%0.0%0.0%
头孢美唑810.0%0.0%100.0%0.0%0.0%
头孢噻肟98612.4%13.1%74.5%0.0%0.0%
头孢他啶153615.1%1.8%83.0%0.0%0.1%
头孢唑肟10.0%100.0%0.0%0.0%0.0%
头孢噻吩40.0%0.0%100.0%0.0%0.0%
环丙沙星145318.7%0.1%81.2%0.0%0.0%
Ertapenem8246.3%0.0%53.7%0.0%0.0%
加替沙星4100.0%0.0%0.0%0.0%0.0%
左旋氧氟沙星149419.7%13.2%67.1%0.0%0.0%
美洛培南120028.3%1.2%70.5%0.0%0.0%
莫西沙星10.0%0.0%0.0%0.0%100.0%
呋喃妥因4831.0%0.4%98.6%0.0%0.0%
氧氟沙星613.3%1.6%95.1%0.0%0.0%
哌拉西林/他唑巴坦154026.9%7.7%65.3%0.0%0.0%
四环素83513.8%1.6%84.7%0.0%0.0%
阿米卡星142325.1%1.5%70.0%0.0%3.4%
氨苄西林9552.7%6.1%91.2%0.0%0.0%
氨苄西林/舒巴坦84517.6%3.0%79.4%0.0%0.0%
阿奇霉素10.0%100.0%0.0%0.0%0.0%
头孢克洛810.0%0.0%100.0%0.0%0.0%
头孢哌酮1212.5%11.6%86.0%0.0%0.0%
头孢哌酮/舒巴坦81638.5%22.8%38.6%0.0%0.1%
头孢替坦3272.4%0.3%97.2%0.0%0.0%
头孢西丁3780.0%0.3%99.7%0.0%0.0%
头孢丙烯810.0%0.0%100.0%0.0%0.0%
头孢曲松10143.6%3.8%91.9%0.0%0.6%
头孢呋辛钠4481.1%3.6%95.3%0.0%0.0%
头孢呋辛酯120.0%33.3%66.7%0.0%0.0%
氯霉素3170.9%0.3%98.7%0.0%0.0%
多粘菌素E21599.5%0.0%0.5%0.0%0.0%
庆大霉素162620.8%1.5%77.7%0.0%0.0%
亚胺培南163531.4%3.4%65.2%0.0%0.0%
美洛西林571.8%1.8%96.5%0.0%0.0%
米诺环素49853.8%21.5%24.7%0.0%0.0%
奈替米星1100.0%0.0%0.0%0.0%0.0%
诺氟沙星8918.0%0.0%82.0%0.0%0.0%
哌拉西林140611.7%5.6%82.7%0.0%0.0%
多粘菌素B44598.4%0.0%1.6%0.0%0.0%
Sulfisoxazole11100.0%0.0%0.0%0.0%0.0%
替卡西林1246.5%1.6%91.9%0.0%0.0%
替卡西林/克拉维酸3069.2%19.0%71.9%0.0%0.0%
妥布霉素84222.2%1.4%76.4%0.0%0.0%
甲氧苄啶40.0%0.0%100.0%0.0%0.0%
复方新诺明103427.0%0.0%64.7%0.0%8.3%
全国大肠埃希菌耐药性统计时间:2014年第1季度-2014年第4季度
药品株数S%I%R%NS%?%
阿莫西林/克拉维酸133652.2%24.1%23.7%0.0%0.0%
氨曲南221445.6%8.6%43.4%0.0%2.4%
头孢唑啉215712.7%3.5%71.8%0.0%12.1%
头孢吡肟275762.7%4.0%33.3%0.0%0.0%
头孢美唑19181.7%2.1%16.2%0.0%0.0%
头孢噻肟205346.6%9.8%42.6%0.0%1.0%
头孢他啶268768.1%4.7%27.1%0.0%0.0%
头孢唑肟8055.0%13.8%31.3%0.0%0.0%
头孢噻吩9116.5%5.5%78.0%0.0%0.0%
环丙沙星235339.2%3.3%57.5%0.0%0.0%
Ertapenem330100.0%0.0%0.0%0.0%0.0%
红霉素20.0%0.0%100.0%0.0%0.0%
加替沙星3122.6%6.5%71.0%0.0%0.0%
左旋氧氟沙星242942.7%4.9%52.4%0.0%0.0%
美洛培南131399.0%0.2%0.8%0.0%0.0%
呋喃妥因92285.1%9.5%5.3%0.0%0.0%
哌拉西林/他唑巴坦241889.2%4.5%6.3%0.0%0.0%
利福平2100.0%0.0%0.0%0.0%0.0%
磺胺甲二唑1650.0%0.0%50.0%0.0%0.0%
四环素93430.2%1.2%68.6%0.0%0.0%
阿米卡星282391.8%1.9%5.7%0.0%0.6%
氨苄西林214310.8%1.8%87.4%0.0%0.0%
氨苄西林/舒巴坦123923.1%25.7%51.3%0.0%0.0%
阿奇霉素20.0%0.0%100.0%0.0%0.0%
阿洛西林1100.0%0.0%0.0%0.0%0.0%
头孢克洛19015.3%2.6%82.1%0.0%0.0%
头孢哌酮20036.0%5.5%58.5%0.0%0.0%
头孢哌酮/舒巴坦143881.1%14.2%4.7%0.0%0.0%
头孢替坦48996.5%1.2%2.2%0.0%0.0%
头孢西丁178076.6%5.3%18.0%0.0%0.1%
头孢丙烯11725.6%0.0%74.4%0.0%0.0%
头孢曲松166834.1%6.5%55.4%0.0%4.1%
头孢呋辛钠209233.6%2.4%64.0%0.0%0.0%
头孢呋辛酯12835.9%6.3%57.8%0.0%0.0%
氯霉素64353.0%6.7%40.3%0.0%0.0%
磷霉素4182.9%0.0%17.1%0.0%0.0%
庆大霉素263347.6%0.6%51.9%0.0%0.0%
亚胺培南281899.5%0.1%0.4%0.0%0.0%
洛美沙星1233.3%8.3%58.3%0.0%0.0%
米诺环素9470.2%16.0%13.8%0.0%0.0%
奈替米星3458.8%0.0%41.2%0.0%0.0%
诺氟沙星13234.8%3.0%62.1%0.0%0.0%
苯唑西林10.0%0.0%100.0%0.0%0.0%
青霉素G20.0%0.0%100.0%0.0%0.0%
哌拉西林228618.0%10.4%71.6%0.0%0.0%
多粘菌素B23193.1%0.0%0.0%0.0%6.9%
Sulfisoxazole12099.2%0.8%0.0%0.0%0.0%
替卡西林10713.1%0.0%86.9%0.0%0.0%
替卡西林/克拉维酸44955.0%22.5%22.5%0.0%0.0%
妥布霉素100050.5%19.9%29.6%0.0%0.0%
甲氧苄啶3122.6%0.0%77.4%0.0%0.0%
复方新诺明145026.3%0.0%66.4%0.0%7.3%
万古霉素250.0%0.0%50.0%0.0%0.0%
请大家移步12楼,看乔乔版主对此数据的分析!
为何耐药性统计只有鲍曼和大肠的?排名第二的肺克和排名第三的铜绿的耐药性统计,老师为何没有放上来啊{:1_4:} 前几位和我院基本一样。 如今互联网发达,如此辛勤采集统计的数据(定期,或不定期更新发布),以行政指令形式让各医疗机构作为临床经验用药参考指导,就妙哉。{:1_17:} 鲍曼不动杆菌的耐药率和我们医院差别好大~~~~~而且鲍曼不动杆菌对头孢唑林、头孢西丁、头孢孟多、头孢呋辛等耐药极高,几乎为天然耐药,但是这个数据头孢西丁敏感率达70%以上,有点不可思议~~~而且按照CLSI很多药都没有必要做~~~ 前面三位跟我们医院是一样的,但是我们第四位就是金黄色葡萄球菌了。
药敏结果差异就比较大了,可以作为经验型用药的一个参考。 谢谢分享学习了。 谢谢分享,可以作为经验用药的一个参考。可以和我院作对比。 前三位跟我们医院是一样的,但是药敏板药物种类好多呀,与我院差别较大! 谢谢老师分享,学习了\(^o^)/~ 前几位和我们医院基本一致 CISI对于鲍曼不动杆菌只规定了以下抗菌药物抑菌环直径折点及MIC解释标准:
青霉素类:哌拉西林、美洛西林、替卡西林
β-内酰胺/β-内酰胺酶抑制剂复合物:氨苄西林/舒巴坦 、哌拉西林/他做把他 、替卡西林/卡拉维酸
头孢类:头孢他啶、头孢吡肟、头孢曲松、头孢噻肟
碳青霉烯类:亚胺培南、美罗培南
脂肽类:多粘菌素B、黏菌素
氨基糖苷类:庆大霉素、妥布霉素、阿米卡星
四环素类:四环素、多西环素、米诺环素
叶酸代谢途径抑制剂:复方新诺明
楼主帖子中鲍曼不动杆菌中的头孢西丁、头孢唑肟、头孢呋辛、呋喃妥因等等,竟然还有阿奇霉素,CISI没有规定的抗菌药物是否敏感、耐药的标准时如何判断的?
老师辛苦了!谢谢分享学习了
关于敏感性我要说几句,这跟医院选取的药物有关,跟是否遵循CLSI要求有关,跟本院的统计方式和上报方式有关,各地区和各医院的多重耐药的敏感程度不一样,与当地抗生素使用有莫大关联,有差异很正常,不必惊讶 澄凤 发表于 2015-2-4 08:23
鲍曼不动杆菌的耐药率和我们医院差别好大~~~~~而且鲍曼不动杆菌对头孢唑林、头孢西丁、头孢孟多、头孢呋辛 ...
一看您的发言就是行家,再看看12楼的说法{:1_9:} 草原星空 发表于 2015-2-4 11:36
一看您的发言就是行家,再看看12楼的说法
不是行家,我不是学检验的,只是和我院相差太大了,鲍曼不动杆菌在我院仅对阿米卡星、复方新诺明等敏感率较高,左氧氟沙星、氨苄西林舒巴坦等中介较多,其余耐药率均在70%以上,基本和2013年CHINET数据差不多吧,乍一看这个“全国的数据”,非常吃惊,也怀疑了自己数据的真实性~~不知来源于哪里?还有就是有些认为人不一定要按照CLSI来做,比如有些医院做了头孢哌酮-舒巴坦、替加环素等,这些都可以,但是说一句不好听的,这些都和一些药商的推动有关系,不过这个就差的太远了,像乔-乔版主一下就能看出来,比如竟然还有阿奇霉素、万古霉素等。 标题很诱人,希望能提供下信息来源(链接或者域名均可) 这个数据来源哪里啊 除了各位老师指出的怎么大肠埃希菌还用大环内酯类做药敏呢 来源于卫生部全国细菌耐药监测网http://quanguo.mohnarin.org/User/Login?typeid=0&returnUrl=%2F 请大家移步12楼.
怎样移,哪位老师指点谢谢!