新的文献,目前没找到原文
Nasal photodisinfection and chlorhexidine wipes decrease surgical site infections: ahistorical control study and propensity analysis.BACKGROUND: Pre-operative decolonization therapy (DcTx) using chlorhexidine (CHG) body washes and/or intranasal mupirocin can reduce surgical site infections (SSIs), but compliance is often suboptimal. AIM: To assess the effectiveness of immediate DcTx using a novel approach of intranasalantimicrobial photodisinfection therapy (PDT) combined with CHG body wipes for the reduction of SSIs. METHODS: Between 1(st) September 2011 and 31(st) August 2012, 3068 elective cardiac, orthopaedic, spinal, vascular, thoracic and neurosurgical patients were treated with CHG in the 24h preceding surgery, and received intranasal PDT in the pre-operative area. SSI surveillance methodology remained unchanged from previous years and patients were followed for one year. Results were compared with those for a four-year historical control group of 12,387 patients as well as those for a concurrent control group of 206 untreated patients. FINDINGS: A significant reduction in the SSI rate was observed between treated patients and the historical control group vs 2.7%, P = 0.0004, odds ratio (OR) 1.73, 95% confidence interval (CI) 1.2815-2.3453]. This significant reduction was maintained on intent-to-treat analysis (P = 0.021, OR 1.37, 95% CI 1.9476-1.7854). Overall compliance with DcTx was 94%. A 1:4 propensity score analysis of matched treated and untreated patients demonstrated that DcTx reduced the risk of SSIs significantly (P = 0.00026, z = 3.65). CONCLUSION: The combination of CHG wipes and PDT immediately before surgery reduced SSIs, achieved excellent compliance, and was easily integrated into the pre-operative routine.
这高大上的东西喔看不懂啊,老师啥意思? PUBMED上面有啊,我们医院跟医学院联网,好像帐号是可以上的,但下载要注册,还没弄过 查到了原文,帮你贴出来。
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