关于抗生素使用和艰难梭菌相关腹泻的风险因素，我们有何教训值得总结？
J Antimicrob Chemother. 2008 Nov 24. LinksWhat have we learned about antimicrobial use and the risks for Clostridium difficile-associated diarrhoea?
关于抗生素使用和艰难梭菌相关腹泻的风险因素，我们有何教训值得总结？
Blondeau JM.
Department of Clinical Microbiology, Royal University Hospital and Saskatoon Health Region, Saskatoon, Saskatchewan, Canada; Departments of Microbiology and Immunology and Pathology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Clostridium difficile is recognized as a major cause of antibiotic-associated diarrhoea and colitis. Antimicrobial agents have been repeatedly recognized as a causative risk for C. difficile-associated diarrhoea (CDAD) and more recently fluoroquinolones have been particularly implicated. Unfortunately, not all reports of antimicrobial associations with CDAD have excluded variables other than antimicrobial use. Prevention of CDAD usually involves infection control interventions and antimicrobial restriction policies may not be fully substantiated by currently available data; however, antimicrobial drug restriction seems prudent in outbreak situations. 这种教训，我们的临床医生是不愿涉足的。他们也许用完了他能想到的所有的抗菌药物，然后也许才能想到此吧:P 谢谢分享{:1_7:}，应该分享经验教训，从中得到启示
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